Evidence map›Paper›PMID 29111438›Full record

ArticleMetabolic engineering2017

Engineering photosynthetic production of L-lysine.

Travis C Korosh, Andrew L Markley, Ryan L Clark, Laura L McGinley, Katherine D McMahon, Brian F Pfleger

Open access · greenAbstract read
In one paragraph

Article in Metabolic engineering, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 51 citations in OpenAlex.

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  9. Development ofFrontiers in microbiology · 2024
    Article
  10. Article
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  13. Translating advances in microbial bioproduction to sustainable biotechnology.Frontiers in bioengineering and biotechnology · 2022
    Review
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  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Travis C KoroshDepartment of Chemical and Biological Engineering, University of Wisconsin-Madison, Madison, WI 53706, United States; Environmental Chemistry and Technology Program, University of Wisconsin-Madison, Madison, WI 53706, United States.
Andrew L MarkleyDepartment of Chemical and Biological Engineering, University of Wisconsin-Madison, Madison, WI 53706, United States.
Ryan L ClarkDepartment of Chemical and Biological Engineering, University of Wisconsin-Madison, Madison, WI 53706, United States.
Laura L McGinleyDepartment of Chemical and Biological Engineering, University of Wisconsin-Madison, Madison, WI 53706, United States.
Katherine D McMahonEnvironmental Chemistry and Technology Program, University of Wisconsin-Madison, Madison, WI 53706, United States; Microbiology Doctoral Training Program, University of Wisconsin-Madison, Madison, WI 53706, United States; Department of Civil and Environmental Engineering, University of Wisconsin-Madison, Madison, WI 53706, United States; Department of Bacteriology, University of Wisconsin-Madison, Madison, WI 53706, United States.
Brian F PflegerDepartment of Chemical and Biological Engineering, University of Wisconsin-Madison, Madison, WI 53706, United States; Microbiology Doctoral Training Program, University of Wisconsin-Madison, Madison, WI 53706, United States. Electronic address: pfleger@engr.wisc.edu.
University of Wisconsin–Madison · US

Funding

BIOTECHNOLOGY TRAINING PROGRAMT32GM008349 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI FOX, BRIAN G · 1989 to 2019
$22.5M
NIGMS NIH HHS T32 GM008349
6 · The paper itself

Abstract

L-lysine and other amino acids are commonly produced through fermentation using strains of heterotrophic bacteria such as Corynebacterium glutamicum. Given the large amount of sugar this process consumes, direct photosynthetic production is intriguing alternative. In this study, we report the development of a cyanobacterium, Synechococcus sp. strain PCC 7002, capable of producing L-lysine with CO

Indexed as

Amino Acid Transport SystemsAspartate KinaseBacterial ProteinsPhotosynthesisSynechococcusCorynebacterium glutamicumLysineAmino Acid Transport SystemsAspartate KinaseBacterial ProteinsLysineAmino acidsCyanobacteriaLysineMetabolic engineeringSynechococcus sp. PCC 7002

Identifiers

PMID29111438
PMCPMC5776718
OpenAlexW2766109133

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.