ArticleDiabetes research and clinical practice2018
Resolution of ketoacidosis in children with new onset diabetes: Evaluation of various definitions.
Article in Diabetes research and clinical practice, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Balanced crystalloids vs. 0.9% saline in pediatric diabetic ketoacidosis: a systematic review and meta-analysis of randomized controlled trials.Frontiers in pediatrics · 2026Pooled it
- 0.9% Saline versus Ringer's lactate as initial fluid in children with diabetic ketoacidosis: a double-blind randomized controlled trial.BMJ open diabetes research & care · 2025Trial
- Effects of Fluid Rehydration Strategy on Correction of Acidosis and Electrolyte Abnormalities in Children With Diabetic Ketoacidosis.Diabetes care · 2021Trial
- Time to resolution of diabetic ketoacidosis in children with type 1 diabetes: a survival analysis of clinical predictors.BMC endocrine disorders · 2026Article
- Risk factors of acute kidney injury in children with diabetic ketoacidosis.BMC nephrology · 2025Article
- Hypertriglyceridemia in New-Onset Type 1 Pediatric Diabetes.Pediatric diabetes · 2025Article
- Time to recovery from diabetic ketoacidosis and its predictors among children with type 1 diabetes at selected governmental hospitals in Addis Ababa, Ethiopia; A five-year retrospective follow-up study.SAGE open medicine · 2025Article
- Early parameter to detect the resolution of pediatric diabetic ketoacidosis.Frontiers in pediatrics · 2025Article
- The role of anion gap normalization time in the management of pediatric diabetic ketoacidosis.Frontiers in pediatrics · 2023Article
- Utility of plasma beta-hydroxybutyrate to define resolution of diabetic ketoacidosis.Pediatric diabetes · 2022Article
- Analysis of the variables involved in the time to resolution of metabolic parameters in adults with diabetic ketoacidosisRevista de la Facultad de Ciencias Medicas (Cordoba, Argentina) · 2022Article
- Clinical characteristics and outcomes of patients with diabetic ketoacidosis of different severity.Medicine · 2020Article
- Acute kidney injury is a common complication in children and adolescents hospitalized for diabetic ketoacidosis.PloS one · 2020Article
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Authors and funding
3 authors.
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Abstract
aimsData are sparse concerning use of serum electrolyte parameters as compared to venous blood gas (VBG) measurements to monitor acid-base status during treatment of diabetic ketoacidosis (DKA). We explored the utility of various parameters to define DKA resolution by investigating the relationship of venous pH (vpH), anion gap (AG), serum bicarbonate (HCO
methodsWe included all patients with NODM presenting with DKA to Boston Children's Hospital from 10/1/07-7/1/13. DKA was defined as serum glucose ≥ 200 mg/dL (11.1 mmol/L) and vpH<7.30; severity as mild <7.30, moderate<7.20, severe<7.10; resolution of DKA as vpH≥7.30 and AG≤18 mmol/L. We used Cox regression to determine time to DKA resolution, and logistic regression to evaluate different serum HCO
results263 patients (133F, mean age 9.9±4.4 years, 74% White) were included. DKA was mild in 134 (51%), moderate in 75 (28%) and severe in 54 (20%). In mild DKA, AG closed after normalization of vpH; in moderate and severe DKA, AG closed before normalization of vpH. HCO
conclusionsDuring management of pediatric DKA, HCO
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