SynthesisRespiratory research2017
Endobronchial one-way valves for treatment of persistent air leaks: a systematic review.
Synthesis in Respiratory research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07184528 (PATCHVALVE Trial), which is not on this map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
PATCHVALVE Trial: A Prospective Evaluation of Blood Patch and Endobronchial Valves for Persistent Air Leaks - Pilot Study
Who cites it
20 citing papers in PubMed, 47 citations in OpenAlex.
- Endoluminal approaches to postoperative air leaks.Journal of thoracic disease · 2026Review
- Endobronchial valves for severe air leak in critically ill children with necrotizing pneumonia requiring extracorporeal membrane oxygenation.Perfusion · 2026Article
- Management of airway hemorrhage with endobronchial valve in patients undergoing pulmonary endarterectomy- an expert center experience: a case report.BMC anesthesiology · 2026Article
- Transforming pulmonary care with applications of endobronchial valves beyond emphysema: a narrative review.Annals of translational medicine · 2025Review
- Article
- Endobronchial Valves for Management of Persistent Air Leaks in Patients With Chronic Lung Disease.Annals of thoracic surgery short reports · 2024Article
- Decellularisation and Characterisation of Porcine Pleura as Bioscaffolds in Tissue Engineering.Journal of tissue engineering and regenerative medicine · 2024Article
- Inverted Placement of Endoscopic One-Way Endobronchial Valve Combined with Gelfoam in the Closure of Bronchopleural Fistula with Empyema in a Mechanically Ventilated Patient: A Case Report.Respiration; international review of thoracic diseases · 2024Article
- Bronchoscopic Endobronchial Valve Therapy for Persistent Air Leaks in COVID-19 Patients Requiring Veno-Venous Extracorporeal Membrane Oxygenation.Journal of clinical medicine · 2023Article
- Off-label use of intrabronchial valves for persistent air leak is safe and effective: a retrospective case analysis.Journal of thoracic disease · 2022Article
- Endobronchial Valve Treatment of Tuberculous Cavities in Patients with Multidrug-Resistant Pulmonary Tuberculosis: A Randomized Clinical Study.Pathogens (Basel, Switzerland) · 2022Article
- Successful use of endobronchial valve for persistent air leak in a patient with COVID-19 and bullous emphysema.BMJ case reports · 2021Article
- Treatment of Bronchopleural and Alveolopleural Fistulas in Acute Respiratory Distress Syndrome With Extracorporeal Membrane Oxygenation, a Case Series and Literature Review.Critical care explorations · 2021Article
- Intrathoracic negative pressure therapy and/or endobronchial valve for pleural empyema minimal invasive management: case series of thirteen patients and review of the literature.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2020Article
- Management of Complications After Lung Resection: Prolonged Air Leak and Bronchopleural Fistula.Thoracic surgery clinics · 2020Review
- One-Way Endobronchial Valves as Management for Persistent Air Leaks: A Preview of What's to Come?American journal of respiratory and critical care medicine · 2019Article
- Management of air leaks post-surgical lung resection.Annals of translational medicine · 2019Review
- Endobronchial valves for persistent air leak all-cause mortality and financial impact: US trend from 2012-2016.Journal of community hospital internal medicine perspectives · 2019Article
- Endobronchial One-Way Valve Therapy Facilitates Weaning from Extracorporeal Membrane Oxygenation in a Patient with ARDS and Persistent Air Leak.Case reports in critical care · 2018Article
- Successful long-term treatment of persistent pulmonary air leak in pneumocystis jirovecii pneumonia by unidirectional endobronchial valves.Respiratory medicine case reports · 2018Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Persistent air leak (PAL) is associated with significant morbidity and mortality, prolonged hospitalization and increased health-care costs. It can arise from a number of conditions, including pneumothorax, necrotizing infection, trauma, malignancies, procedural interventions and complications after thoracic surgery. Numerous therapeutic options, including noninvasive and invasive techniques, are available to treat PALs. Recently, endobronchial one-way valves have been used to treat PAL. We conducted a systematic review based on studies retrieved from PubMed, EMbase and Cochrane library. We also did a hand-search in the bibliographies of relevant articles for additional studies. 34 case reports and 10 case series comprising 208 patients were included in our review. Only 4 patients were children, most of the patients were males. The most common underlying disease was COPD, emphysema and cancer. The most remarkable cause was pneumothorax. The upper lobes were the most frequent locations of air leaks. Complete resolution was gained within less than 24 h in majority of patients. Complications were migration or expectoration of valves, moderate oxygen desaturation and infection of related lung. No death related to endobronchial one-way valves implantation has been found. The use of endobronchial one-way valve adds to the armamentarium for non-invasive treatments of challenging PAL, especially those with difficulties of anesthesia, poor condition and high morbidity. Nevertheless, prospective randomized control trials with large sample should be needed to further evaluate the effects and safety of endobronchial one-way valve implantation in the treatment of PAL.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.