Evidence map›Paper›PMID 29110244›Full record

ArticleObesity surgery2018

The Effect of 6 and 12 months Duodenal-Jejunal Bypass Liner Treatment on Obesity and Type 2 Diabetes: a Crossover Cohort Study.

Selwyn van Rijn, Bark Betzel, Charlotte de Jonge, David P J van Dijk, Ignace M Janssen, Frits J Berends, Nicole D Bouvy, Jan Willem M Greve

Open access · hybridAbstract read
In one paragraph

Article in Obesity surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Overview on the endoscopic treatment for obesity: A review.World journal of gastroenterology · 2023
    Review
  3. Ockham's razor and the metabolic syndrome.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2021
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Selwyn van RijnDepartment of General Surgery, Maastricht University Medical Center, Maastricht, The Netherlands.ORCID 0000-0002-8568-9788
Bark BetzelDepartment of General Surgery, Rijnstate Medical Center, Arnhem, The Netherlands.
Charlotte de JongeDepartment of General Surgery, Zuyderland Medical Center, Heerlen-Sittard, The Netherlands.
David P J van DijkDepartment of General Surgery, Maastricht University Medical Center, Maastricht, The Netherlands.
Ignace M JanssenDepartment of General Surgery, Rijnstate Medical Center, Arnhem, The Netherlands.
Frits J BerendsDepartment of General Surgery, Rijnstate Medical Center, Arnhem, The Netherlands.
Nicole D BouvyDepartment of General Surgery, Maastricht University Medical Center, Maastricht, The Netherlands.
Jan Willem M GreveDepartment of General Surgery, Zuyderland Medical Center, Heerlen-Sittard, The Netherlands. j.greve@zuyderland.nl.
Maastricht University · NLRijnstate Hospital · NLZuyderland Medisch Centrum · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this research was to study the duodenal-jejunal bypass liner (DJBL) treatment for obesity and type 2 diabetes mellitus (T2DM) in patients after dietary treatment in a cross-over design.

backgroundDJBL treatment has been proven effective for treatment of obesity and T2DM. However, data on safety and efficacy of a 12-month DJBL treatment is limited.

methodsIn 2014, our research group reported on a multicenter randomized clinical trial. Patients were randomized to DJBL or dietary treatment (control group). Twenty-eight patients crossed over after their dietary treatment and received up to 12 months of DJBL treatment. Patient visits were conducted at baseline, during DJBL treatment (1 week, 1-6, 9, 12 months) and 6 months after removal of the liner. Patients underwent a standard physical examination, blood sampling, assessment of adverse events, nutritional and diabetes counseling, and a standardized meal tolerance test.

resultsOf the 28 patients included in this study, 24 patients completed 6 months of treatment. Eighteen patients were extended to 12 months of DJBL treatment; 13 patients completed this treatment period. After 6 months of DJBL treatment, a significant increase in excess weight loss (EWL) and decrease in weight, BMI, HbA1c, fasting glucose, cholesterol, HDL and LDL improved significantly. After 12 months of DJBL treatment, these parameters stabilized.

conclusionsThe DJBL is an effective, minimally invasive treatment option. Even after successful treatment with dietary restrictions, the DJBL is still capable of significantly reducing weight and improving cardiovascular and type 2 diabetes mellitus parameters in obese patients.

Indexed as

Bariatric SurgeryDiabetes Mellitus, Type 2Obesity, MorbidCross-Over StudiesDuodenumHumansJejunumProstheses and ImplantsTreatment OutcomeWeight LossAbdominal surgeryDuodenal-jejunal bypass linerObesityType 2 diabetes mellitus

Identifiers

PMID29110244
PMCPMC5968053
OpenAlexW2767307208

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.