ArticleCognitive, affective & behavioral neuroscience2017
Integrated cross-network connectivity of amygdala, insula, and subgenual cingulate associated with facial emotion perception in healthy controls and remitted major depressive disorder.
Article in Cognitive, affective & behavioral neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Balancing act: Neural correlates of affect dysregulation in youth depression and substance use - A systematic review of functional neuroimaging studies.Developmental cognitive neuroscience · 2020Pooled it
- Anticipation of monetary reward in amygdala, insula, caudate are predictors of pleasure sensitivity to d-Amphetamine administration.Drug and alcohol dependence · 2020Trial
- Sleep Architecture and Risk-Taking in Adolescents and Young Adults: Independent Contributions of REM Sleep, Sigma Activity, and Morning Cortisol.Behavioral sciences (Basel, Switzerland) · 2026Article
- Manipulating facial musculature with functional electrical stimulation as an intervention for major depressive disorder: a focused search of literature for a proposal.Journal of neuroengineering and rehabilitation · 2023Review
- Facial emotion recognition in adolescent depression: The role of childhood traumas, emotion regulation difficulties, alexithymia and empathy.Indian journal of psychiatry · 2023Article
- A longitudinal mediation study of peer victimization and resting-state functional connectivity as predictors of development of adolescent psychopathology.Frontiers in psychiatry · 2023Article
- Transdiagnostic phenotypes of compulsive behavior and associations with psychological, cognitive, and neurobiological affective processing.Translational psychiatry · 2022Article
- Individual Differences in Hemispheric Emotional Valence by Computerized Test Correlate with Lateralized Differences in Nucleus Accumbens, Hippocampal and Amygdala Volumes.Psychology research and behavior management · 2022Article
- Using Network Parcels and Resting-State Networks to Estimate Correlates of Mood Disorder and Related Research Domain Criteria Constructs of Reward Responsiveness and Inhibitory Control.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2022Article
- Enriching activities during childhood are associated with variations in functional connectivity patterns later in life.Neurobiology of aging · 2021Article
- Effects of Serial Ketamine Infusions on Corticolimbic Functional Connectivity in Major Depression.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2021Article
- The relationship between resting-state functional connectivity, antidepressant discontinuation and depression relapse.Scientific reports · 2020Article
- Occipital Magnocellular VEP Non-linearities Show a Short Latency Interaction Between Contrast and Facial Emotion.Frontiers in human neuroscience · 2020Article
- Cognitive control neuroimaging measures differentiate between those with and without future recurrence of depression.NeuroImage. Clinical · 2018Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
Emotion perception deficits could be due to disrupted connectivity of key nodes in the salience and emotion network (SEN), including the amygdala, subgenual anterior cingulate cortex (sgACC), and insula. We examined SEN resting-state (rs-)fMRI connectivity in rMDD in relation to Facial Emotion Perception Test (FEPT) performance. Fifty-two medication-free people ages 18 to 23 years participated. Twenty-seven had major depressive disorder (MDD) in remission (rMDD, 10 males), as MDD is associated with emotion perception deficits and alterations in rsfMRI. Twenty-five healthy controls (10 males) also participated. Participants completed the FEPT during fMRI, in addition to an 8-minute eyes-open resting-state scan. Seed regions of interest were defined in the amygdala, anterior insula and sgACC. Multiple regression analyses co-varied diagnostic group, sex and movement parameters. Emotion perception accuracy was positively associated with connectivity between amygdala seeds and regions primarily in the SEN and cognitive control network (CCN), and also the default mode network (DMN). Accuracy was also positively associated with connectivity between the sgACC seeds and other SEN regions, and the DMN, particularly for the right sgACC. Connectivity negatively associated with emotion perception was mostly with regions outside of these three networks, other than the left insula and part of the DMN. This study is the first to our knowledge to demonstrate relationships between facial emotion processing and resting-state connectivity with SEN nodes and between SEN nodes and regions located within other neural networks.
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