Evidence map›Paper›PMID 29109952›Full record

ArticleFrontiers in veterinary science2017

Is TB Testing Associated With Increased Blood Interferon-Gamma Levels?

Aideen E Kennedy, Jim O'Mahony, Noel Byrne, John MacSharry, Riona G Sayers

Abstract read
In one paragraph

Article in Frontiers in veterinary science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. The Occurrence ofAnimals : an open access journal from MDPI · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Aideen E KennedyAnimal and Bioscience Research Department, Animal and Grassland Research and Innovation Centre, Teagasc, Fermoy, Ireland.
Jim O'MahonyDepartment of Biological Sciences, Cork Institute of Technology, Cork, Ireland.
Noel ByrneAnimal and Bioscience Research Department, Animal and Grassland Research and Innovation Centre, Teagasc, Fermoy, Ireland.
John MacSharryAlimentary Pharmabiotic Centre, Biosciences Institute, University College Cork, Cork, Ireland.
Riona G SayersAnimal and Bioscience Research Department, Animal and Grassland Research and Innovation Centre, Teagasc, Fermoy, Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Republic of Ireland reports a relatively low prevalence of Johne's disease (JD) compared to international counterparts. Postulated reasons for this include a lower average herd size and a grass-based production system. Ireland also engages in high levels of bovine tuberculosis (bTB) testing. As interferon-gamma (IFN-γ) is believed to play a key role in protecting against JD, it is our hypothesis that administration of purified protein derivative (PPD), as part of the bTB test, is associated with a systemic increase in IFN-γ production, which may potentially limit clinical progression of the disease. We studied 265 cows (202 Friesian and 63 "Non-Friesian," e.g., JerseyX, Norwegian Red) to assess IFN-γ levels and

Indexed as

ELISAinterferon-gammaJohne’s diseasepurified protein derivativeTB test

Identifiers

PMID29109952
PMCPMC5660059

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.