Evidence map›Paper›PMID 29109893›Full record

ArticleTurkish journal of ophthalmology2017

Correlation of Corneal Endothelial Cell Density with Corneal Tomographic Parameters in Eyes with Keratoconus.

Banu Bozkurt, Mevlüt Yılmaz, Ali Meşen, Ümit Kamış, Bengü Ekinci Köktekir, Süleyman Okudan

Open access · diamondAbstract read
In one paragraph

Article in Turkish journal of ophthalmology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Update on Contact Lens Treatment of KeratoconusTurkish journal of ophthalmology · 2020
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Banu BozkurtSelçuk University Faculty of Medicine, Department of Ophthalmology, Konya, Turkey.
Mevlüt YılmazDr. Munif İslamoğlu State Hospital, Ophthalmology Clinic, Kastamonu, Turkey.
Ali MeşenSelçuk University Faculty of Medicine, Department of Ophthalmology, Konya, Turkey.
Ümit KamışDünyagöz Hospital, Ophthalmology Clinic, Konya, Turkey.
Bengü Ekinci KöktekirSelçuk University Faculty of Medicine, Department of Ophthalmology, Konya, Turkey.
Süleyman OkudanSelçuk University Faculty of Medicine, Department of Ophthalmology, Konya, Turkey.
Dünyagöz Hospital · TRKastamonu University · TRSamsun University · TRSelçuk University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo examine changes in corneal endothelial cell density (ECD) in different stages of keratoconus and evaluate its correlation with corneal tomographic parameters. MATERIALS AND

methodsTwo hundred six patients with keratoconus were enrolled in the study. Corneal topography was performed by Sirius (CSO, Italy), which has a rotating Scheimpflug camera and a Placido disc topographer. Automatic endothelial analysis was done with the non-contact endothelial microscope (20x probe) of Confoscan-4 (NIDEK, Japan). The eyes were classified into stages based on steepest keratometric value as follows: mild <45 D; moderate 45-52 D; severe >52 D and according to thinnest cornea thickness (TCT) as <400 μm, 400-450 μm, and >450 μm. Tomographic and endothelial cell parameters were compared among the groups using Kruskal-Wallis test and the correlations between them were analyzed using Spearman correlation.

resultsThe study included 391 eyes of 100 male (24.29±7.7 years, range 11-47 years) and 106 female (26.26±7.5 years, range 13-45 years) patients (p=0.07). Mean ECD values were 2628±262 cells/mm

conclusionAs endothelial cell numbers seem to decrease with the progression of keratoconus, specular/confocal microscopy screening should be carried out, especially in eyes with advanced stages and corneas with TCT <400 µm.

Indexed as

cornea endothelial cell densitycorneal tomographyKeratoconusmorphological changesspecular microscopy

Identifiers

PMID29109893
PMCPMC5661174
OpenAlexW2765931103

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.