Evidence map›Paper›PMID 29109793›Full record

ArticleTheranostics2017

Acute Inflammatory Response Following Increased Blood-Brain Barrier Permeability Induced by Focused Ultrasound is Dependent on Microbubble Dose.

Dallan McMahon, Kullervo Hynynen

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 166 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
166citing papers in PubMed, 1 pooled it
10.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

166 citing papers in PubMed, 1 synthesis or guideline pooled it, 258 citations in OpenAlex.

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106 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Dallan McMahonUniversity of Toronto, Department of Medical Biophysics, Toronto, M4N 3M5, Canada.
Kullervo HynynenUniversity of Toronto, Department of Medical Biophysics, Toronto, M4N 3M5, Canada.
Sunnybrook Health Science Centre · CAUniversity of Toronto · CA

Funding

Ultrasound Therapy Delivery Through Intact SkullR01EB003268 · NIBIB · SUNNYBROOK & WOMEN'S COLL HLTH SCIS CTR · PI HYNYNEN, KULLERVO · 2003 to 2020
$8.2M
CIHR FRN 119312NIBIB NIH HHS R01 EB003268
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

MicrobubblesAnimalsBlood-Brain BarrierBrainGadoliniumInflammationMagnetic Resonance ImagingNF-kappa BRatsRats, Sprague-DawleyGadoliniumNF-kappa Bblood-brain barrierfocused ultrasoundinflammationmicrobubbles.

Identifiers

PMID29109793
PMCPMC5667420
OpenAlexW2754309875

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.