Evidence map›Paper›PMID 29109784›Full record

ArticleTheranostics2017

Multimodal Assessment of Mesenchymal Stem Cell Therapy for Diabetic Vascular Complications.

Jamila Hedhli, Christian J Konopka, Sarah Schuh, Hannah Bouvin, John A Cole, Heather D Huntsman, Kristopher A Kilian, Iwona T Dobrucki, Marni D Boppart, Lawrence W Dobrucki

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. Article
  6. Stem Cell-Based Therapy for Diabetic Foot Ulcers.Frontiers in cell and developmental biology · 2022
    Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. BioMed research international · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Jamila HedhliBeckman Institute for Advanced Science and Technology, Urbana, IL.
Christian J KonopkaBeckman Institute for Advanced Science and Technology, Urbana, IL.
Sarah SchuhDepartment of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL.
Hannah BouvinBeckman Institute for Advanced Science and Technology, Urbana, IL.
John A ColeDepartment of Physics, University of Illinois at Urbana-Champaign, Urbana, IL.
Heather D HuntsmanBeckman Institute for Advanced Science and Technology, Urbana, IL.
Kristopher A KilianDepartment of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL.
Iwona T DobruckiBeckman Institute for Advanced Science and Technology, Urbana, IL.
Marni D BoppartBeckman Institute for Advanced Science and Technology, Urbana, IL.
Lawrence W DobruckiBeckman Institute for Advanced Science and Technology, Urbana, IL.
University of Illinois Urbana-Champaign · US

Funding

Tissue microenvironment (TIMe) training programT32EB019944 · NIBIB · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI BHARGAVA, ROHIT, GASKINS, REX · 2016 to 2025
$1.9M
NIBIB NIH HHS T32 EB019944
6 · The paper itself

Abstract

Peripheral arterial disease (PAD) is a debilitating complication of diabetes mellitus (DM) that leads to thousands of injuries, amputations, and deaths each year. The use of mesenchymal stem cells (MSCs) as a regenerative therapy holds the promise of regrowing injured vasculature, helping DM patients live healthier and longer lives. We report the use of muscle-derived MSCs to treat surgically-induced hindlimb ischemia in a mouse model of type 1 diabetes (DM-1). We serially evaluate several facets of the recovery process, including

Indexed as

Mesenchymal Stem Cell TransplantationAnimalsDiabetic AngiopathiesGene Expression RegulationImage Processing, Computer-AssistedIntegrin alphaVbeta3IschemiaMesenchymal Stem CellsMice, Inbred C57BLMusclesNeovascularization, PhysiologicPerfusionPeripheral Arterial DiseasePositron Emission Tomography Computed TomographyPostmortem ChangesProteomeIntegrin alphaVbeta3ProteomeAngiogenesisDiabetesDimeric-cRGDMultimodal imagingMuscle-derived mesenchymal stem cells (mMSCs).Peripheral arterial disease (PAD)PET-CT

Identifiers

PMID29109784
PMCPMC5667411
OpenAlexW2755775022

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.