ArticleExpert review of endocrinology & metabolism2017
Understanding the impact of hypoglycemia on the cardiovascular system.
Article in Expert review of endocrinology & metabolism, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- Epidermal growth factor outperforms placebo in the treatment of diabetic foot ulcer: a meta-analysis.F1000Research · 2022Pooled it
- Hypoglycaemia leads to a delayed increase in platelet and coagulation activation markers in people with type 2 diabetes treated with metformin only: Results from a stepwise hypoglycaemic clamp study.Diabetes, obesity & metabolism · 2020Trial
- Relationship between hypoglycaemia, cardiovascular outcomes, and empagliflozin treatment in the EMPA-REG OUTCOME® trial.European heart journal · 2020Trial
- The impact of short-term intensive fasting on physical health and gut microbiota in obese individuals.Frontiers in nutrition · 2026Article
- Fatigue in Final Hour of an Ironman Triathlon with Absence of Carbohydrate Supplementation: A Retrospective Case Study.International journal of exercise science · 2026Article
- Interplay of glycated hemoglobin and traditional risk factors for the risk of atherosclerotic cardiovascular disease and all-cause mortality in people without diabetes.Cardiovascular diabetology · 2025Observational
- Review
- The impact of three months of adjuvant yoga intervention on glycemic control among adolescents with type 1 diabetes: a randomized control trial.Diabetology & metabolic syndrome · 2025Article
- Diabetic ketoacidosis and hyperosmolar hyperglycemic state in diabetes patients with heart failure: insight from the National inpatient sample.BMC cardiovascular disorders · 2025Article
- Glycemic Variability and Its Association with Traditional Glycemic Control Biomarkers in Patients with Type 1 Diabetes: A Cross-Sectional, Multicenter Study.Journal of clinical medicine · 2025Article
- Article
- A Comparative Analysis of Clinical Features of Diabetes Mellitus Type 2 With Respect to Duration of Diabetes.Cureus · 2024Article
- Health-related quality of life in Chinese individuals with type 2 diabetes mellitus: a multicenter cross-sectional study.Health and quality of life outcomes · 2023Article
- Hypoglycemia induces vascular endothelial dysfunction in subjects with normal glucose tolerance.Scientific reports · 2022Article
- Low HbA1c levels and all-cause or cardiovascular mortality among people without diabetes: the US National Health and Nutrition Examination Survey 1999-2015.International journal of epidemiology · 2021Article
- A nationwide cohort study for comparative vascular safety of long-acting insulin analogue versus intermediate-acting human insulin in type 2 diabetes.Scientific reports · 2021Article
- Variability in Annual Fasting Glucose and the Risk of Peripheral Artery Disease in Patients with Diabetes Mellitus.Diabetes, metabolic syndrome and obesity : targets and therapy · 2021Article
- Prevalence and incidence of type 1 diabetes in the world: a systematic review and meta-analysis.Health promotion perspectives · 2020Review
- Physiological monitoring of the complex multimorbid heart failure patient - diabetes and monitoring glucose control.European heart journal supplements : journal of the European Society of Cardiology · 2019Article
- Severe hypoglycemia and the risk of cardiovascular disease and mortality in type 2 diabetes: a nationwide population-based cohort study.Cardiovascular diabetology · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
introductionHypoglycemia occurs commonly in insulin requiring individuals with either Type 1 or Type 2 Diabetes. AREAS COVERED: This article will review recent information on the pro-inflammatory and pro-atherothrombotic effects of hypoglycemia. Additionally, effects of hypoglycemia on arrhythmogenic potential and arterial endothelial dysfunction will be discussed. Effects of hypoglycemia on cardiovascular morbidity and mortality from large clinical studies in Type 1 and Type 2 DM will also be reviewed. EXPERT COMMENTARY: The relative and absolute risk of severe hypoglycemia leading to death and serious adverse events in both cardiovascular and other organ systems has been highlighted following the publication of recent large clinical trials focused on glucose control and outcomes. It would be helpful if future studies could develop broader end points to include minor and moderate hypoglycemia as well as more robust methods for capturing hypoglycemia contemporaneously with adverse events. In addition, perhaps consideration of including hypoglycemia as a primary outcome, may help identify the possible cause and effect of hypoglycemia on cardiovascular morbidity and mortality.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.