Evidence map›Paper›PMID 29109476›Full record

ArticleNature microbiology2017

The major targets of acute norovirus infection are immune cells in the gut-associated lymphoid tissue.

Katrina R Grau, Alexa N Roth, Shu Zhu, Abel Hernandez, Natacha Colliou, Bayli B DiVita, Drake T Philip, Cara Riffe, Benoit Giasson, Shannon M Wallet and 2 more

Abstract read
In one paragraph

Article in Nature microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 92 citations in OpenAlex.

  1. Article
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  7. Review
  8. Article
  9. Article
  10. In Vitro Models for Investigating Intestinal Host-Pathogen Interactions.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Development and validation of an efficient nomogram for risk assessment of norovirus infection in pediatric patients.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2022
    Article
  18. Article
  19. Article
  20. Review

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Katrina R GrauDepartment of Molecular Genetics & Microbiology, Emerging Pathogens Institute, Center for Inflammation and Mucosal Immunology, College of Medicine, University of Florida, Gainesville, FL, USA.
Alexa N RothDepartment of Molecular Genetics & Microbiology, Emerging Pathogens Institute, Center for Inflammation and Mucosal Immunology, College of Medicine, University of Florida, Gainesville, FL, USA.
Shu ZhuDepartment of Molecular Genetics & Microbiology, Emerging Pathogens Institute, Center for Inflammation and Mucosal Immunology, College of Medicine, University of Florida, Gainesville, FL, USA.
Abel HernandezDepartment of Molecular Genetics & Microbiology, Emerging Pathogens Institute, Center for Inflammation and Mucosal Immunology, College of Medicine, University of Florida, Gainesville, FL, USA.
Natacha ColliouDepartment of Infectious Diseases & Immunology, Center for Inflammation & Mucosal Immunology, College of Medicine, University of Florida, Gainesville, FL, USA.
Bayli B DiVitaDepartment of Oral Biology, College of Dentistry, University of Florida, Gainesville, FL, USA.
Drake T PhilipDepartment of Molecular Genetics & Microbiology, Emerging Pathogens Institute, Center for Inflammation and Mucosal Immunology, College of Medicine, University of Florida, Gainesville, FL, USA.
Cara RiffeDepartment of Neuroscience, Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, USA.
Benoit GiassonDepartment of Neuroscience, Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, USA.
Shannon M WalletDepartment of Oral Biology, College of Dentistry, University of Florida, Gainesville, FL, USA.
Mansour MohamadzadehDepartment of Infectious Diseases & Immunology, Center for Inflammation & Mucosal Immunology, College of Medicine, University of Florida, Gainesville, FL, USA.
Stephanie M KarstDepartment of Molecular Genetics & Microbiology, Emerging Pathogens Institute, Center for Inflammation and Mucosal Immunology, College of Medicine, University of Florida, Gainesville, FL, USA. skarst@ufl.edu.ORCID http://orcid.org/0000-0003-0406-4637
University of Florida · US

Funding

BASIC MICROBIOLOGY &INFECTIOUS DISEASEST32AI007110 · NIAID · UNIVERSITY OF FLORIDA · PI Stephanie M Karst · 1985 to 2026
$4.3M
Identification of Host and Viral Determinants of Human Norovirus B cell InfectionR01AI123144 · NIAID · UNIVERSITY OF FLORIDA · PI KARST, STEPHANIE M · 2017 to 2021
$2.3M
Role of Intestinal Bacteria in Human Norovirus InfectionR01AI116892 · NIAID · UNIVERSITY OF FLORIDA · PI KARST, STEPHANIE M · 2015 to 2019
$1.8M
Lack of protective immunity to murine norovirus infectionR01AI081921 · NIAID · UNIVERSITY OF FLORIDA · PI KARST, STEPHANIE M · 2010 to 2013
$1.2M
NIAID NIH HHS R01 AI081921NIAID NIH HHS R01 AI116892NIAID NIH HHS R01 AI123144NIAID NIH HHS T32 AI007110
6 · The paper itself

Abstract

Noroviruses are the leading cause of food-borne gastroenteritis outbreaks and childhood diarrhoea globally, estimated to be responsible for 200,000 deaths in children each year

Indexed as

AnimalsB-LymphocytesCaliciviridae InfectionsCell LineCell SurvivalDendritic CellsDisease Models, AnimalDuodenumFemaleImmunity, MucosalIntestinal MucosaIntestinesMaleMiceMice, Inbred C57BLNorovirus

Identifiers

PMID29109476
PMCPMC5705318
OpenAlexW2765276615

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.