Evidence map›Paper›PMID 29109461›Full record

ArticleScientific reports2017

Oral administration of cannabis with lipids leads to high levels of cannabinoids in the intestinal lymphatic system and prominent immunomodulation.

Atheer Zgair, Jong Bong Lee, Jonathan C M Wong, Dhiaa A Taha, Jehan Aram, Daisy Di Virgilio, Joshua W McArthur, Yu-Kit Cheng, Ivo M Hennig, David A Barrett and 3 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 2 pooled it
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 2 syntheses or guidelines pooled it, 124 citations in OpenAlex.

  1. Immunomodulatory Potential of Cannabidiol in Multiple Sclerosis: a Systematic Review.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2021
    Pooled it
  2. Pharmacological evidence of medicinal cannabis in oncology: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019
    Pooled it
  3. Trial
  4. Review
  5. Article
  6. Review
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  8. Article
  9. ComparativeFrontiers in toxicology · 2026
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Transport functions of intestinal lymphatic vessels.Nature reviews. Gastroenterology & hepatology · 2025
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

Atheer ZgairSchool of Pharmacy, University of Nottingham, Nottingham, NG7 2RD, United Kingdom.
Jong Bong LeeSchool of Pharmacy, University of Nottingham, Nottingham, NG7 2RD, United Kingdom.
Jonathan C M WongSchool of Pharmacy, University of Nottingham, Nottingham, NG7 2RD, United Kingdom.ORCID 0000-0001-5660-7256
Dhiaa A TahaSchool of Pharmacy, University of Nottingham, Nottingham, NG7 2RD, United Kingdom.
Jehan AramDivision of Clinical Neuroscience, University of Nottingham and Queen's Medical Centre, Nottingham, NG7 2UH, United Kingdom.
Daisy Di VirgilioSchool of Pharmacy, University of Nottingham, Nottingham, NG7 2RD, United Kingdom.
Joshua W McArthurSchool of Pharmacy, University of Nottingham, Nottingham, NG7 2RD, United Kingdom.
Yu-Kit ChengSchool of Pharmacy, University of Nottingham, Nottingham, NG7 2RD, United Kingdom.
Ivo M HennigNottingham City Hospital, Nottingham University Hospitals NHS Trust, Nottingham, NG5 1PB, United Kingdom.
David A BarrettSchool of Pharmacy, University of Nottingham, Nottingham, NG7 2RD, United Kingdom.ORCID 0000-0001-6900-9474
Peter M FischerSchool of Pharmacy, University of Nottingham, Nottingham, NG7 2RD, United Kingdom.
Cris S ConstantinescuDivision of Clinical Neuroscience, University of Nottingham and Queen's Medical Centre, Nottingham, NG7 2UH, United Kingdom.
Pavel GershkovichSchool of Pharmacy, University of Nottingham, Nottingham, NG7 2RD, United Kingdom. Pavel.Gershkovich@nottingham.ac.uk.ORCID 0000-0003-3136-0933
University of Nottingham · GBNottingham University Hospitals NHS Trust · GB

Funding

Wellcome TrustWellcome Trust 109186/Z/15/Z
6 · The paper itself

Abstract

Cannabidiol (CBD) and ∆

Indexed as

Administration, OralAnimalsCannabinoidsDronabinolHumansImmunomodulationImmunosuppression TherapyIntestinesLipidsLymphatic SystemMaleMiceRatsRats, Sprague-DawleyCannabinoidsDronabinolLipids

Identifiers

PMID29109461
PMCPMC5674070
OpenAlexW2766413288

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.