ArticleProceedings of the National Academy of Sciences of the United States of America2017
Sea anemone model has a single Toll-like receptor that can function in pathogen detection, NF-κB signal transduction, and development.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 96 citations in OpenAlex.
- Review
- Is a Commensal Here, a Pathogen There? Genotype Specific Responses by the Sea Anemone Nematostella vectensis to Vibrio Species.Molecular ecology · 2026Article
- c-JUN controls microbial colonization via selective phagocytosis in the sea anemone Nematostella.Nature communications · 2026Article
- Unique Transcriptional Responses by the Sea Anemone Nematostella vectensis to Individual Bacteria: Roles for Bacterial Species, Secreted Products and the Microbiome.Molecular ecology · 2026Article
- NF-κB: A Diverse and Multifunctional Transcription Factor in Holozoans.Molecular biology and evolution · 2026Review
- Runaway coral-algal dysbiosis may be responsible for rapid coral tissue loss.Scientific reports · 2026Article
- Genomic analysis reveals broad adaptability of coral-killing sponge (Terpios hoshinota) under environmental stress.BMC genomics · 2025Article
- Patterns of pathogenesis in innate immunity: insights from C. elegans.Nature reviews. Immunology · 2025Review
- A Network Approach to White Band Disease Challenged Staghorn CoralEcology and evolution · 2025Article
- Influence of Temperature and Saline Conditions on Bacteria Naturally Associated With the Cnidarian HostInternational journal of microbiology · 2025Article
- Chromosome-level genome assembly of the sacoglossan sea slug Elysia timida (Risso, 1818).BMC genomics · 2024Article
- Induction of apoptosis by double-stranded RNA was present in the last common ancestor of cnidarian and bilaterian animals.PLoS pathogens · 2024Article
- Updated single cell reference atlas for the starlet anemone Nematostella vectensis.Frontiers in zoology · 2024Article
- Evolution of the Major Components of Innate Immunity in Animals.Journal of molecular evolution · 2024Review
- Sequential host-bacteria and bacteria-bacteria interactions determine the microbiome establishment of Nematostella vectensis.Microbiome · 2023Article
- Starvation decreases immunity and immune regulatory factor NF-κB in the starlet sea anemone Nematostella vectensis.Communications biology · 2023Article
- Body-Plan Reorganization in a Sponge Correlates with Microbiome Change.Molecular biology and evolution · 2023Article
- Bivalves Present the Largest and Most Diversified Repertoire of Toll-Like Receptors in the Animal Kingdom, Suggesting Broad-Spectrum Pathogen Recognition in Marine Waters.Molecular biology and evolution · 2023Article
- The localization of Toll and Imd pathway and complement system components and their response to Vibrio infection in the nemertean Lineus ruber.BMC biology · 2023Article
- Synergistic and antagonistic interactions of oxybenzone and ocean acidification: new insight into vulnerable cellular processes in non-calcifying anthozoans.Frontiers in physiology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In organisms from insects to vertebrates, Toll-like receptors (TLRs) are primary pathogen detectors that activate downstream pathways, specifically those that direct expression of innate immune effector genes. TLRs also have roles in development in many species. The sea anemone
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.