Evidence map›Paper›PMID 29109274›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Near-infrared remotely triggered drug-release strategies for cancer treatment.

Amanda M Goodman, Oara Neumann, Kamilla Nørregaard, Luke Henderson, Mi-Ran Choi, Susan E Clare, Naomi J Halas

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

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  10. Chemically-Controlled Ultrafast Photothermal Response in Plasmonic Nanostructured Assemblies.The journal of physical chemistry. C, Nanomaterials and interfaces · 2022
    Article
  11. Review
  12. Review
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  15. DNA Nanostructures and DNA-Functionalized Nanoparticles for Cancer Theranostics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020
    Review
  16. Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Amanda M GoodmanDepartment of Chemistry, Rice University, Houston, TX 77005.
Oara NeumannDepartment of Electrical and Computer Engineering, Rice University, Houston, TX 77005.
Kamilla NørregaardThe Niels Bohr Institute, University of Copenhagen, 2100 Copenhagen, Denmark.
Luke HendersonDepartment of Chemistry, Rice University, Houston, TX 77005.
Mi-Ran ChoiDepartment of Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611.
Susan E ClareDepartment of Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611.
Naomi J HalasDepartment of Chemistry, Rice University, Houston, TX 77005; halas@rice.edu.

Funding

Role of Mitochondrial CYP2E1 in Chemical Exposure-Driven NeurodegenerationF32ES027306 · NIEHS · DUKE UNIVERSITY · PI HARTMAN, JESSICA HELENE · 2016 to 2018
$171k
NIEHS NIH HHS 27306C0004
6 · The paper itself

Abstract

Remotely controlled, localized drug delivery is highly desirable for potentially minimizing the systemic toxicity induced by the administration of typically hydrophobic chemotherapy drugs by conventional means. Nanoparticle-based drug delivery systems provide a highly promising approach for localized drug delivery, and are an emerging field of interest in cancer treatment. Here, we demonstrate near-IR light-triggered release of two drug molecules from both DNA-based and protein-based hosts that have been conjugated to near-infrared-absorbing Au nanoshells (SiO

Indexed as

Infrared RaysAntineoplastic AgentsBreast NeoplasmsCell Line, TumorDNADocetaxelDrug Delivery SystemsDrug LiberationFemaleGoldHumansLapatinibLasersNanoshellsQuinazolinesSerum Albumin, HumanAntineoplastic AgentsDNADocetaxelGoldLapatinibQuinazolinesSerum Albumin, HumanTaxoidscancerchemotherapydrug releasenanoparticlenear-infrared

Identifiers

PMID29109274
PMCPMC5703316

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.