Trial reportThe Journal of neuroscience : the official journal of the Society for Neuroscience2017
Sleep Deprivation Promotes Habitual Control over Goal-Directed Control: Behavioral and Neuroimaging Evidence.
Trial report in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed.
- Effects of sleep deprivation on food-related Pavlovian-instrumental transfer: a randomized crossover experiment.Scientific reports · 2024Trial
- Trial
- Sleep regulates drug seeking and relapse - a perspective.Molecular psychiatry · 2026Review
- Understanding Lifestyle Dissonance: A Neurobiological Narrative to Strengthen Preventive Health Behavior.European journal of neurology · 2026Review
- Nucleus accumbens dynamics in food reward seeking and regulation by sleep.Translational psychiatry · 2025Article
- Memory control deficits in the sleep-deprived human brain.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Exploring the link between anticipatory outcome encoding in the brain and goal-directed behavior during outcome devaluation.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Digital Multidomain Lifestyle Intervention for Community-Dwelling Older Adults: A Mixed Methods Evaluation.International journal of public health · 2025Article
- Prior-Night Sleep Predicts Next-Day Sedentary Behavior as a Function of Work Duration in Public Safety Telecommunicators.Occupational health science · 2024Article
- The impact of REM sleep loss on human brain connectivity.Translational psychiatry · 2024Article
- Review
- Sleep Duration and Executive Function in Adults.Current neurology and neuroscience reports · 2023Review
- Day-to-day directional relationships between sleep duration and negative affect.Journal of psychosomatic research · 2023Article
- Experimental verification and identifying biomarkers related to insomnia.Frontiers in neurology · 2023Article
- Abnormal cerebellar-prefrontal cortical pathways in obstructive sleep apnea with/without mild cognitive impairment.Frontiers in neuroscience · 2022Article
- Clinical Effect of Electroacupuncture on Acute Sleep Deprivation and Event-Related Potential Affecting the Inhibition Control of the Brain: Study Protocol for a Randomized Controlled Trial.Frontiers in neurology · 2022Article
- Article
- Hydrogen gas post-conditioning alleviates cognitive dysfunction and anxiety-like behavior in a rat model of subarachnoid hemorrhage.Experimental and therapeutic medicine · 2021Article
- Dopamine D1 and D2 receptors are distinctly associated with rest-activity rhythms and drug reward.The Journal of clinical investigation · 2021Article
- At the intersection of sleep deficiency and opioid use: mechanisms and therapeutic opportunities.Translational research : the journal of laboratory and clinical medicine · 2021Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sleep is one of the most fundamental processes of life, playing an important role in the regulation of brain function. The long-term lack of sleep can cause memory impairments, declines in learning ability, and executive dysfunction. In the present study, we evaluated the effects of sleep deprivation on instrumental learning behavior, particularly goal-directed and habitual actions in humans, and investigated the underlying neural mechanisms. Healthy college students of either gender were enrolled and randomly divided into sleep deprivation group and sleep control group. fMRI data were collected. We found that one night of sleep deprivation led to greater responsiveness to stimuli that were associated with devalued outcomes in the slips-of-action test, indicating a deficit in the formation of goal-directed control and an overreliance on habits. Furthermore, sleep deprivation had no effect on the expression of acquired goal-directed action. The level of goal-directed action after sleep deprivation was positively correlated with baseline working memory capacity. The neuroimaging data indicated that goal-directed learning mainly recruited the ventromedial PFC (vmPFC), the activation of which was less pronounced during goal-directed learning after sleep deprivation. Activation of the vmPFC during goal-directed learning during training was positively correlated with the level of goal-directed action performance. The present study suggests that people rely predominantly on habits at the expense of goal-directed control after sleep deprivation, and this process involves the vmPFC. These results contribute to a better understanding of the effects of sleep loss on decision-making.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.