ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2017
The consequences of sequence erosion in the evolution of recombination hotspots.
Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 28 citations in OpenAlex.
- Complete human recombination maps.Nature · 2025Article
- Natural variation in the zinc-finger-encoding exon of Prdm9 affects hybrid sterility phenotypes in mice.Genetics · 2024Article
- The chromatin determinants and Ph1 gene effect at wheat sites with contrasting recombination frequency.Journal of advanced research · 2023Article
- Evolution of the recombination regulator PRDM9 in minke whales.BMC genomics · 2022Article
- Article
- Chromosome-wide characterization of meiotic noncrossovers (gene conversions) in mouse hybrids.Genetics · 2021Article
- Sexual dimorphism in the meiotic requirement for PRDM9: A mammalian evolutionary safeguard.Science advances · 2020Article
- Heterogeneous transposable elements as silencers, enhancers and targets of meiotic recombination.Chromosoma · 2019Review
- PRDM9 Diversity at Fine Geographical Scale Reveals Contrasting Evolutionary Patterns and Functional Constraints in Natural Populations of House Mice.Molecular biology and evolution · 2019Article
- PRDM9 forms a trimer by interactions within the zinc finger array.Life science alliance · 2019Article
- LDJump: Estimating variable recombination rates from population genetic data.Molecular ecology resources · 2019Article
- The impact of poly-A microsatellite heterologies in meiotic recombination.Life science alliance · 2019Article
- Mapping Recombination Rate on the Autosomal Chromosomes Based on the Persistency of Linkage Disequilibrium Phase Among Autochthonous Beef Cattle Populations in Spain.Frontiers in genetics · 2019Article
- Where to Cross Over? Defining Crossover Sites in Plants.Frontiers in genetics · 2018Review
- Coevolution between transposable elements and recombination.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017Review
- Recombination: the good, the bad and the variable.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017Article
- The impact of recombination on human mutation load and disease.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017Review
- Low recombination rates in sexual species and sex-asex transitions.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 2 countries.
Funding
Abstract
Meiosis is initiated by a double-strand break (DSB) introduced in the DNA by a highly controlled process that is repaired by recombination. In many organisms, recombination occurs at specific and narrow regions of the genome, known as recombination hotspots, which overlap with regions enriched for DSBs. In recent years, it has been demonstrated that conversions and mutations resulting from the repair of DSBs lead to a rapid sequence evolution at recombination hotspots eroding target sites for DSBs. We still do not fully understand the effect of this erosion in the recombination activity, but evidence has shown that the binding of
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.