Evidence map›Paper›PMID 29109208›Full record

ArticleCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne2017

The Cedar Project: mortality among young Indigenous people who use drugs in British Columbia.

Kate Jongbloed, Margo E Pearce, Sherri Pooyak, David Zamar, Vicky Thomas, Lou Demerais, Wayne M Christian, Earl Henderson, Richa Sharma, Alden H Blair and 4 more

Open access · goldAbstract read
In one paragraph

Article in CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. The hepatitis C epidemic in Canada: An overview of recent trends in surveillance, injection drug use, harm reduction and treatment.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2021
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Need for equity in treatment of substance use among Indigenous people in Canada.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2017
    Article
  17. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 1 country.

Kate JongbloedSchool of Population and Public Health (Jongbloed, Sharma, Blair, Schechter, Spittal), Department of Chemical and Biological Engineering (Zamar), and Faculty of Medicine, Division of Gastroenterology (Yoshida), The University of British Columbia; Canadian HIV Trials Network (Pearce); Canadian Aboriginal AIDS Network (Pooyak [Cree]); The Cedar Project, BC Children's Hospital Research Institute (Thomas [Wuikinuxv Nation]), BC Children's Hospital; Vancouver Native Health Society (Demerais [Cree, Métis]), Vancouver, BC; Splatsin te Secwepemc (Christian [Splatsin te Secwepemc]); Department of First Nations Studies (Henderson [Cree, Métis]), University of Northern British Columbia, Prince George, BC; Division of Gastroenterology (Yoshida), Vancouver General Hospital, Vancouver, BC.
Margo E PearceSchool of Population and Public Health (Jongbloed, Sharma, Blair, Schechter, Spittal), Department of Chemical and Biological Engineering (Zamar), and Faculty of Medicine, Division of Gastroenterology (Yoshida), The University of British Columbia; Canadian HIV Trials Network (Pearce); Canadian Aboriginal AIDS Network (Pooyak [Cree]); The Cedar Project, BC Children's Hospital Research Institute (Thomas [Wuikinuxv Nation]), BC Children's Hospital; Vancouver Native Health Society (Demerais [Cree, Métis]), Vancouver, BC; Splatsin te Secwepemc (Christian [Splatsin te Secwepemc]); Department of First Nations Studies (Henderson [Cree, Métis]), University of Northern British Columbia, Prince George, BC; Division of Gastroenterology (Yoshida), Vancouver General Hospital, Vancouver, BC.
Sherri PooyakSchool of Population and Public Health (Jongbloed, Sharma, Blair, Schechter, Spittal), Department of Chemical and Biological Engineering (Zamar), and Faculty of Medicine, Division of Gastroenterology (Yoshida), The University of British Columbia; Canadian HIV Trials Network (Pearce); Canadian Aboriginal AIDS Network (Pooyak [Cree]); The Cedar Project, BC Children's Hospital Research Institute (Thomas [Wuikinuxv Nation]), BC Children's Hospital; Vancouver Native Health Society (Demerais [Cree, Métis]), Vancouver, BC; Splatsin te Secwepemc (Christian [Splatsin te Secwepemc]); Department of First Nations Studies (Henderson [Cree, Métis]), University of Northern British Columbia, Prince George, BC; Division of Gastroenterology (Yoshida), Vancouver General Hospital, Vancouver, BC.
David ZamarSchool of Population and Public Health (Jongbloed, Sharma, Blair, Schechter, Spittal), Department of Chemical and Biological Engineering (Zamar), and Faculty of Medicine, Division of Gastroenterology (Yoshida), The University of British Columbia; Canadian HIV Trials Network (Pearce); Canadian Aboriginal AIDS Network (Pooyak [Cree]); The Cedar Project, BC Children's Hospital Research Institute (Thomas [Wuikinuxv Nation]), BC Children's Hospital; Vancouver Native Health Society (Demerais [Cree, Métis]), Vancouver, BC; Splatsin te Secwepemc (Christian [Splatsin te Secwepemc]); Department of First Nations Studies (Henderson [Cree, Métis]), University of Northern British Columbia, Prince George, BC; Division of Gastroenterology (Yoshida), Vancouver General Hospital, Vancouver, BC.
Vicky ThomasSchool of Population and Public Health (Jongbloed, Sharma, Blair, Schechter, Spittal), Department of Chemical and Biological Engineering (Zamar), and Faculty of Medicine, Division of Gastroenterology (Yoshida), The University of British Columbia; Canadian HIV Trials Network (Pearce); Canadian Aboriginal AIDS Network (Pooyak [Cree]); The Cedar Project, BC Children's Hospital Research Institute (Thomas [Wuikinuxv Nation]), BC Children's Hospital; Vancouver Native Health Society (Demerais [Cree, Métis]), Vancouver, BC; Splatsin te Secwepemc (Christian [Splatsin te Secwepemc]); Department of First Nations Studies (Henderson [Cree, Métis]), University of Northern British Columbia, Prince George, BC; Division of Gastroenterology (Yoshida), Vancouver General Hospital, Vancouver, BC.
Lou DemeraisSchool of Population and Public Health (Jongbloed, Sharma, Blair, Schechter, Spittal), Department of Chemical and Biological Engineering (Zamar), and Faculty of Medicine, Division of Gastroenterology (Yoshida), The University of British Columbia; Canadian HIV Trials Network (Pearce); Canadian Aboriginal AIDS Network (Pooyak [Cree]); The Cedar Project, BC Children's Hospital Research Institute (Thomas [Wuikinuxv Nation]), BC Children's Hospital; Vancouver Native Health Society (Demerais [Cree, Métis]), Vancouver, BC; Splatsin te Secwepemc (Christian [Splatsin te Secwepemc]); Department of First Nations Studies (Henderson [Cree, Métis]), University of Northern British Columbia, Prince George, BC; Division of Gastroenterology (Yoshida), Vancouver General Hospital, Vancouver, BC.
Wayne M ChristianSchool of Population and Public Health (Jongbloed, Sharma, Blair, Schechter, Spittal), Department of Chemical and Biological Engineering (Zamar), and Faculty of Medicine, Division of Gastroenterology (Yoshida), The University of British Columbia; Canadian HIV Trials Network (Pearce); Canadian Aboriginal AIDS Network (Pooyak [Cree]); The Cedar Project, BC Children's Hospital Research Institute (Thomas [Wuikinuxv Nation]), BC Children's Hospital; Vancouver Native Health Society (Demerais [Cree, Métis]), Vancouver, BC; Splatsin te Secwepemc (Christian [Splatsin te Secwepemc]); Department of First Nations Studies (Henderson [Cree, Métis]), University of Northern British Columbia, Prince George, BC; Division of Gastroenterology (Yoshida), Vancouver General Hospital, Vancouver, BC.
Earl HendersonSchool of Population and Public Health (Jongbloed, Sharma, Blair, Schechter, Spittal), Department of Chemical and Biological Engineering (Zamar), and Faculty of Medicine, Division of Gastroenterology (Yoshida), The University of British Columbia; Canadian HIV Trials Network (Pearce); Canadian Aboriginal AIDS Network (Pooyak [Cree]); The Cedar Project, BC Children's Hospital Research Institute (Thomas [Wuikinuxv Nation]), BC Children's Hospital; Vancouver Native Health Society (Demerais [Cree, Métis]), Vancouver, BC; Splatsin te Secwepemc (Christian [Splatsin te Secwepemc]); Department of First Nations Studies (Henderson [Cree, Métis]), University of Northern British Columbia, Prince George, BC; Division of Gastroenterology (Yoshida), Vancouver General Hospital, Vancouver, BC.
Richa SharmaSchool of Population and Public Health (Jongbloed, Sharma, Blair, Schechter, Spittal), Department of Chemical and Biological Engineering (Zamar), and Faculty of Medicine, Division of Gastroenterology (Yoshida), The University of British Columbia; Canadian HIV Trials Network (Pearce); Canadian Aboriginal AIDS Network (Pooyak [Cree]); The Cedar Project, BC Children's Hospital Research Institute (Thomas [Wuikinuxv Nation]), BC Children's Hospital; Vancouver Native Health Society (Demerais [Cree, Métis]), Vancouver, BC; Splatsin te Secwepemc (Christian [Splatsin te Secwepemc]); Department of First Nations Studies (Henderson [Cree, Métis]), University of Northern British Columbia, Prince George, BC; Division of Gastroenterology (Yoshida), Vancouver General Hospital, Vancouver, BC.
Alden H BlairSchool of Population and Public Health (Jongbloed, Sharma, Blair, Schechter, Spittal), Department of Chemical and Biological Engineering (Zamar), and Faculty of Medicine, Division of Gastroenterology (Yoshida), The University of British Columbia; Canadian HIV Trials Network (Pearce); Canadian Aboriginal AIDS Network (Pooyak [Cree]); The Cedar Project, BC Children's Hospital Research Institute (Thomas [Wuikinuxv Nation]), BC Children's Hospital; Vancouver Native Health Society (Demerais [Cree, Métis]), Vancouver, BC; Splatsin te Secwepemc (Christian [Splatsin te Secwepemc]); Department of First Nations Studies (Henderson [Cree, Métis]), University of Northern British Columbia, Prince George, BC; Division of Gastroenterology (Yoshida), Vancouver General Hospital, Vancouver, BC.
Eric M YoshidaSchool of Population and Public Health (Jongbloed, Sharma, Blair, Schechter, Spittal), Department of Chemical and Biological Engineering (Zamar), and Faculty of Medicine, Division of Gastroenterology (Yoshida), The University of British Columbia; Canadian HIV Trials Network (Pearce); Canadian Aboriginal AIDS Network (Pooyak [Cree]); The Cedar Project, BC Children's Hospital Research Institute (Thomas [Wuikinuxv Nation]), BC Children's Hospital; Vancouver Native Health Society (Demerais [Cree, Métis]), Vancouver, BC; Splatsin te Secwepemc (Christian [Splatsin te Secwepemc]); Department of First Nations Studies (Henderson [Cree, Métis]), University of Northern British Columbia, Prince George, BC; Division of Gastroenterology (Yoshida), Vancouver General Hospital, Vancouver, BC.
Martin T SchechterSchool of Population and Public Health (Jongbloed, Sharma, Blair, Schechter, Spittal), Department of Chemical and Biological Engineering (Zamar), and Faculty of Medicine, Division of Gastroenterology (Yoshida), The University of British Columbia; Canadian HIV Trials Network (Pearce); Canadian Aboriginal AIDS Network (Pooyak [Cree]); The Cedar Project, BC Children's Hospital Research Institute (Thomas [Wuikinuxv Nation]), BC Children's Hospital; Vancouver Native Health Society (Demerais [Cree, Métis]), Vancouver, BC; Splatsin te Secwepemc (Christian [Splatsin te Secwepemc]); Department of First Nations Studies (Henderson [Cree, Métis]), University of Northern British Columbia, Prince George, BC; Division of Gastroenterology (Yoshida), Vancouver General Hospital, Vancouver, BC.
Patricia M SpittalSchool of Population and Public Health (Jongbloed, Sharma, Blair, Schechter, Spittal), Department of Chemical and Biological Engineering (Zamar), and Faculty of Medicine, Division of Gastroenterology (Yoshida), The University of British Columbia; Canadian HIV Trials Network (Pearce); Canadian Aboriginal AIDS Network (Pooyak [Cree]); The Cedar Project, BC Children's Hospital Research Institute (Thomas [Wuikinuxv Nation]), BC Children's Hospital; Vancouver Native Health Society (Demerais [Cree, Métis]), Vancouver, BC; Splatsin te Secwepemc (Christian [Splatsin te Secwepemc]); Department of First Nations Studies (Henderson [Cree, Métis]), University of Northern British Columbia, Prince George, BC; Division of Gastroenterology (Yoshida), Vancouver General Hospital, Vancouver, BC spittal@sm.hivnet.ubc.ca.
Cedar Project Partnership
University of Northern British Columbia · CACanadian Aboriginal AIDS Network · CAUniversity of British Columbia · CAVancouver Native Health Society · CAHIV Legal Network · CAVancouver General Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundYoung Indigenous people, particularly those involved in the child welfare system, those entrenched in substance use and those living with HIV or hepatitis C, are dying prematurely. We report mortality rates among young Indigenous people who use drugs in British Columbia and explore predictors of mortality over time.

methodsWe analyzed data collected every 6 months between 2003 and 2014 by the Cedar Project, a prospective cohort study involving young Indigenous people who use illicit drugs in Vancouver and Prince George, BC. We calculated age-standardized mortality ratios using Indigenous and Canadian reference populations. We identified predictors of mortality using time-dependent Cox proportional hazard regression.

resultsAmong 610 participants, 40 died between 2003 and 2014, yielding a mortality rate of 670 per 100 000 person-years. Young Indigenous people who used drugs were 12.9 (95% confidence interval [CI] 9.2-17.5) times more likely to die than all Canadians the same age and were 7.8 (95% CI 5.6-10.6) times more likely to die than Indigenous people with Status in BC. Young women and those using drugs by injection were most affected. The leading causes of death were overdose (

interpretationYoung Indigenous people using drugs in BC are dying at an alarming rate, particularly young women and those using injection drugs. These deaths likely reflect complex intersections of historical and present-day injustices, substance use and barriers to care.

Indexed as

AdolescentBritish ColumbiaCause of DeathCohort StudiesConfidence IntervalsDrug OverdoseFemaleHepatitis CHumansIndians, North AmericanMaleProspective StudiesRegression AnalysisSubstance Abuse, IntravenousSuicideYoung Adult

Identifiers

PMID29109208
PMCPMC5675541
OpenAlexW2767746113

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.