Evidence map›Paper›PMID 29109185›Full record

ArticleJournal of bacteriology2018

Genome-Wide Screens Reveal New Gene Products That Influence Genetic Competence in Streptococcus mutans.

Robert C Shields, Greg O'Brien, Natalie Maricic, Alexandria Kesterson, Megan Grace, Stephen J Hagen, Robert A Burne

Open access · bronzeAbstract read
In one paragraph

Article in Journal of bacteriology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Genomic instability and biofilm determinants inbioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Characterization of MreCD inJournal of oral microbiology · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Transposon mutagenesis in oralJournal of oral microbiology · 2022
    Review
  10. The transcription regulator BrsR serves as a network hub of natural competence protein-protein interactions inProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Expanding the Vocabulary of Peptide Signals inFrontiers in cellular and infection microbiology · 2019
    Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Robert C ShieldsDepartment of Oral Biology, College of Dentistry, University of Florida, Gainesville, Florida, USA.ORCID 0000-0002-8823-9504
Greg O'BrienDepartment of Physics, University of Florida, Gainesville, Florida, USA.
Natalie MaricicDepartment of Oral Biology, College of Dentistry, University of Florida, Gainesville, Florida, USA.
Alexandria KestersonDepartment of Oral Biology, College of Dentistry, University of Florida, Gainesville, Florida, USA.
Megan GraceDepartment of Oral Biology, College of Dentistry, University of Florida, Gainesville, Florida, USA.
Stephen J HagenDepartment of Physics, University of Florida, Gainesville, Florida, USA.ORCID 0000-0002-3373-5033
Robert A BurneDepartment of Oral Biology, College of Dentistry, University of Florida, Gainesville, Florida, USA rburne@dental.ufl.edu.ORCID 0000-0002-4234-0316
University of Florida · US

Funding

Comprehensive Training Program in Oral BiologyT90DE021990 · NIDCR · UNIVERSITY OF FLORIDA · PI Jose A Lemos · 2011 to 2026
$8.2M
GENETICS AND PHYSIOLOGY OF ORAL BIOFILMSR01DE013239 · NIDCR · UNIVERSITY OF ROCHESTER · PI BURNE, ROBERT A · 1999 to 2019
$6.6M
Environmental regulation of gene expression dissected by microfluidicsR01DE023339 · NIDCR · UNIVERSITY OF FLORIDA · PI BURNE, ROBERT A, HAGEN, STEPHEN JAMES · 2014 to 2018
$1.9M
NIDCR NIH HHS R01 DE013239NIDCR NIH HHS R01 DE023339NIDCR NIH HHS T90 DE021990
6 · The paper itself

Abstract

A network of genes and at least two peptide signaling molecules tightly control when

Indexed as

Genome, BacterialGenome-Wide Association StudyBacterial ProteinsDNA Transformation CompetenceGene Expression Regulation, BacterialMutationStreptococcus mutansBacterial ProteinsComX/SigXpeptide signalssingle-cell behaviorsstress tolerancetransposon mutagenesis

Identifiers

PMID29109185
PMCPMC5738738
OpenAlexW2767753884

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.