Evidence map›Paper›PMID 29109175›Full record

ArticleInfection and immunity2018

The Streptococcus agalactiae Stringent Response Enhances Virulence and Persistence in Human Blood.

Thomas A Hooven, Andrew J Catomeris, Maryam Bonakdar, Luke J Tallon, Ivette Santana-Cruz, Sandra Ott, Sean C Daugherty, Hervé Tettelin, Adam J Ratner

Open access · hybridAbstract read
In one paragraph

Article in Infection and immunity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 38 citations in OpenAlex.

  1. Microbiology (Reading, England) · 2026
    Article
  2. Article
  3. Review
  4. Arginine at the host-pathogen interface.Infection and immunity · 2025
    Review
  5. Article
  6. A CRISPRi library screen in group BInfection and immunity · 2025
    Article
  7. Identification of glyoxalase A in group BInfection and immunity · 2025
    Article
  8. Identification of Glyoxalase A in Group BbioRxiv : the preprint server for biology · 2024
    Article
  9. A CRISPRi Library Screen in Group BbioRxiv : the preprint server for biology · 2024
    Article
  10. Article
  11. Group BJournal of bacteriology · 2024
    Article
  12. Review
  13. Recent Advances in Bacterial Persistence Mechanisms.International journal of molecular sciences · 2023
    Review
  14. Article
  15. Article
  16. Nitric Oxide Production and Effects in Group BPathogens (Basel, Switzerland) · 2022
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Thomas A HoovenDepartment of Pediatrics, Columbia University, New York, New York, USA.
Andrew J CatomerisDepartment of Pediatrics, New York University, New York, New York, USA.
Maryam BonakdarDepartment of Pediatrics, New York University, New York, New York, USA.
Luke J TallonInstitute for Genome Sciences, University of Maryland, Baltimore, Maryland, USA.
Ivette Santana-CruzInstitute for Genome Sciences, University of Maryland, Baltimore, Maryland, USA.
Sandra OttInstitute for Genome Sciences, University of Maryland, Baltimore, Maryland, USA.
Sean C DaughertyInstitute for Genome Sciences, University of Maryland, Baltimore, Maryland, USA.
Hervé TettelinInstitute for Genome Sciences, University of Maryland, Baltimore, Maryland, USA.
Adam J RatnerDepartment of Pediatrics, New York University, New York, New York, USA Adam.Ratner@nyumc.org.ORCID http://orcid.org/0000-0003-1761-794X
University of Maryland, Baltimore · USNew York University · USColumbia University · US

Funding

Pediatric Scientist Development Program (PSDP) [K12]K12HD000850 · NICHD · YALE UNIVERSITY · PI Sallie R. Permar · 1987 to 2026
$44.1M
Gardnerella vaginalis: toxin production and pathogenesisR01AI092743 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI RATNER, ADAM JONATHAN · 2011 to 2015
$2.0M
DNase For Prevention Of Reproductive Tract Infections In PregnancyR33AI098654 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI RATNER, ADAM JONATHAN · 2014 to 2016
$1.6M
R21 Orphan nuclear receptorsR21AI111020 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI RATNER, ADAM JONATHAN · 2014 to 2015
$451k
NIAID NIH HHS R01 AI092743NIAID NIH HHS R21 AI111020NIAID NIH HHS R33 AI098654NICHD NIH HHS K12 HD000850
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ArginineBacterial ProteinsCell CommunicationGene Expression Regulation, BacterialGenes, BacterialGenetic FitnessHemolysin ProteinsHumansHydrolasesOperonPerforinStreptococcal InfectionsStreptococcus agalactiaeTranscriptomeVirulenceArgininearginine deiminaseBacterial ProteinsHemolysin ProteinsHydrolasesPerforinbloodstream infectionsStreptococcus agalactiaeTn-seq

Identifiers

PMID29109175
PMCPMC5736797
OpenAlexW2767797639

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.