Evidence map›Paper›PMID 29109168›Full record

ArticleAntimicrobial agents and chemotherapy2018

Risk Factors and Outcomes for Ineffective Empiric Treatment of Sepsis Caused by Gram-Negative Pathogens: Stratification by Onset of Infection.

Scott T Micek, Nicholas Hampton, Marin Kollef

Erratum issuedOpen access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 27 citations in OpenAlex.

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  15. A multidrug-resistant microorganism infection risk prediction model: development and validation in an emergency medicine population.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2020
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Scott T Micek *Center for Health Outcomes Research and Education, St. Louis College of Pharmacy, St. Louis, Missouri, USA.
Nicholas Hampton *Center for Clinical Excellence, BJC Healthcare, St. Louis, Missouri, USA.
Marin Kollef *Division of Pulmonary and Critical Care Medicine, Washington University School of Medicine, St. Louis, Missouri, USA kollefm@wustl.edu.
BJC HealthCare · USUniversity of Health Sciences and Pharmacy · USWashington University in St. Louis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sepsis and septic shock remain serious consequences of infections, with reported mortality rates in excess of 40 percent. Timely antibiotic therapy in cases of sepsis and septic shock is recognized as an important determinant of outcome. However, the administration of ineffective empirical treatment (IET) (an initial antibiotic regimen that is not active against the identified pathogen[s] based on

Indexed as

Anti-Bacterial AgentsBacteremiaFemaleGram-Negative BacteriaGram-Negative Bacterial InfectionsHospital MortalityHumansMaleMiddle AgedRisk FactorsShock, SepticAnti-Bacterial AgentsGram-negativesepsis

Identifiers

PMID29109168
PMCPMC5740380
OpenAlexW2767270468

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.