Evidence map›Paper›PMID 29109159›Full record

ArticleAntimicrobial agents and chemotherapy2018

Overtreatment of Asymptomatic Candiduria among Hospitalized Patients: a Multi-institutional Study.

David M Jacobs, Thomas J Dilworth, Nicholas D Beyda, Anthony M Casapao, Dana R Bowers

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Adherence to evidence-based guidelines for the management of candiduria in a tertiary care center in Riyadh: A retrospective cross-sectional study.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2026
    Article
  3. Article
  4. Asymptomatic Candiduria due toCase reports in infectious diseases · 2026
    Article
  5. Article
  6. Article
  7. Invasive Candidiasis in the Intensive Care Unit: Where Are We Now?Journal of fungi (Basel, Switzerland) · 2025
    Review
  8. Review
  9. Review
  10. Article
  11. Augmented Enterocyte Damage DuringFrontiers in cellular and infection microbiology · 2022
    Article
  12. Templated microbiology comments with candiduria to enhance antimicrobial stewardship.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2022
    Article
  13. Article
  14. Management of candiduria in hospitalized patients: a single-center study on the implementation of IDSA guidelines and factors affecting clinical decisions.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2021
    Article
  15. Candida urinary tract infections in adults.World journal of urology · 2020
    Review
  16. Review
  17. Performance of yeast-like cell counting (YLCC) using the Sysmex UF-1000i for clinical candiduria screening.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2019
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 1 country.

David M JacobsUniversity at Buffalo School of Pharmacy and Pharmaceutical Sciences, Buffalo, New York, USA dmjacobs@buffalo.edu.ORCID 0000-0001-9240-7067
Thomas J DilworthWheaton Franciscan Healthcare, Milwaukee, Wisconsin, USA.
Nicholas D BeydaUniversity of Houston College of Pharmacy, Houston, Texas, USA.
Anthony M CasapaoHusson University School of Pharmacy, Bangor, Maine, USA.
Dana R BowersKingman Regional Medical Center, Kingman, Arizona, USA.
Husson University · USRegional Medical Center · USUniversity at Buffalo, State University of New York · USUniversity of Houston · USWheaton Franciscan Healthcare · US

Funding

University of Buffalo Clinical and Translational Science Institute - Supplement SchulyerUL1TR001412 · NCATS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI MURPHY, TIMOTHY F · 2015 to 2024
$33.8M
Institutional Career DevelopmentKL2TR001413 · NCATS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI DUBOCOVICH, MARGARITA L · 2015 to 2024
$4.2M
NCATS NIH HHS KL2 TR001413NCATS NIH HHS UL1 TR001412
6 · The paper itself

Abstract

Candiduria is common in hospitalized patients, and asymptomatic candiduria contributes to antifungal overuse. The guidelines for management of asymptomatic candiduria do not recommend antifungal use, but rather the elimination of predisposing factors. It is unknown whether these recommendations are being followed. The primary objective of this study was to characterize candiduria management among hospitalized patients. This was a retrospective cohort study of a random sample of 305 hospitalized patients with candiduria at four U.S. medical centers from January 2010 to December 2013. Patients were classified as asymptomatic or symptomatic based on established criteria, and data were collected by chart review. Infectious Diseases Society of America (IDSA) treatment guideline adherence and its association with clinical outcomes, including candiduria recurrence (short- and long-term) and 30-day readmission, were assessed. Eighty percent of patients were classified as having asymptomatic candiduria. Overall, 143 (47%) patients were not managed according to recommended guidelines, including 105/243 (43%) in the asymptomatic candiduria group and 38/62 (61%) in the symptomatic group (

Indexed as

Asymptomatic InfectionsInappropriate PrescribingMedical OveruseAgedAntifungal AgentsCandidaCandidiasisFemaleFluconazoleHumansMaleMicafunginRetrospective StudiesUrinary Tract InfectionsAntifungal AgentsFluconazoleMicafunginCandidaepidemiologyIDSA guidelinesurinary tract infections

Identifiers

PMID29109159
PMCPMC5740329
OpenAlexW2767879368

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.