Evidence map›Paper›PMID 29109153›Full record

ArticleThe Journal of biological chemistry2018

Structure-function analyses reveal key features in

Catherine F M Bowden, Anson C K Chan, Emily J W Li, Angelé L Arrieta, Lindsay D Eltis, Michael E P Murphy

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 51 citations in OpenAlex.

  1. Cryo-EM provides insight into how thebioRxiv : the preprint server for biology · 2026
    Article
  2. Hemoglobin receptor redundancy inJournal of structural biology: X · 2025
    Article
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  6. Molecular basis of hemoglobin binding and heme removal inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
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  12. Review
  13. The Shr receptor fromProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  14. Article
  15. Article
  16. Article
  17. Cryo-EM structures of staphylococcal IsdB bound to human hemoglobin reveal the process of heme extraction.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  18. Pirates of the haemoglobin.Microbial cell (Graz, Austria) · 2022
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Catherine F M BowdenDepartment of Microbiology and Immunology, Life Sciences Institute, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada.
Anson C K ChanDepartment of Microbiology and Immunology, Life Sciences Institute, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada.
Emily J W LiDepartment of Microbiology and Immunology, Life Sciences Institute, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada.
Angelé L ArrietaDepartment of Microbiology and Immunology, Life Sciences Institute, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada.
Lindsay D EltisDepartment of Microbiology and Immunology, Life Sciences Institute, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada.
Michael E P MurphyDepartment of Microbiology and Immunology, Life Sciences Institute, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada. Electronic address: Michael.Murphy@ubc.ca.
University of British Columbia · CA

Funding

X-ray Absorption Spectroscopy (XAS) pp.711-759P41GM103393 · NIGMS · STANFORD UNIVERSITY · PI HODGSON, KEITH O · 2012 to 2019
$30.6M
CIHR MOP-49597NIGMS NIH HHS P41 GM103393
6 · The paper itself

Abstract

IsdB is a receptor on the surface of the bacterial pathogen

Indexed as

Carrier ProteinsCation Transport ProteinsCrystallography, X-RayHaptoglobinsHemeHeme-Binding ProteinsHemeproteinsHemoglobinsHumansIronProtein ConformationProtein UnfoldingReceptors, Cell SurfaceStaphylococcus aureusStructure-Activity RelationshipCarrier ProteinsCation Transport ProteinsHaptoglobinsHemeHeme-Binding ProteinsHemeproteinsHemoglobinsIronIsdB protein, Staphylococcus aureusReceptors, Cell Surfacecrystal structurehemehemoglobinironStaphylococcus aureus (S. aureus)

Identifiers

PMID29109153
PMCPMC5766928
OpenAlexW2767767832

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.