Evidence map›Paper›PMID 29109097›Full record

ReviewCancer genomics & proteomics

Role of Melt Curve Analysis in Interpretation of Nutrigenomics' MicroRNA Expression Data.

Farid E Ahmed, Mostafa M Gouda, Laila A Hussein, Nancy C Ahmed, Paul W Vos, Mahmoud A Mohammad

Open access · diamondAbstract readReview
In one paragraph

Review in Cancer genomics & proteomics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
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  4. Evaluation of Proanthocyanidins from Kiwi Leaves (Antioxidants (Basel, Switzerland) · 2022
    Article
  5. Review
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  14. Possible Role ofJournal of International Society of Preventive & Community Dentistry
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Farid E AhmedGEM Tox Labs, Institute for Research in Biotechnology, Greenville, NC, U.S.A. gemtoxconsultants@yahoo.com.
Mostafa M GoudaDepartment of Nutrition & Food Science, National Research Centre, Dokki, Cairo, Egypt.
Laila A HusseinDepartment of Nutrition & Food Science, National Research Centre, Dokki, Cairo, Egypt.
Nancy C AhmedGEM Tox Labs, Institute for Research in Biotechnology, Greenville, NC, U.S.A.
Paul W VosDepartment of Biostatistics, College of Allied Health Sciences, East Carolina University, Greenville, NC, U.S.A.
Mahmoud A MohammadUSDA/ARS Children's Nutrition Research, Houston, TX, U.S.A.
National Research Centre · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This article illustrates the importance of melt curve analysis (MCA) in interpretation of mild nutrogenomic micro(mi)RNA expression data, by measuring the magnitude of the expression of key miRNA molecules in stool of healthy human adults as molecular markers, following the intake of Pomegranate juice (PGJ), functional fermented sobya (FS), rich in potential probiotic lactobacilli, or their combination. Total small RNA was isolated from stool of 25 volunteers before and following a three-week dietary intervention trial. Expression of 88 miRNA genes was evaluated using Qiagen's 96 well plate RT

Indexed as

AdultFemaleGene Expression ProfilingHumansMaleMicroRNAsNutrigenomicsResearch DesignYoung AdultMicroRNAsBiomarkersDNAfermented sobyafoodmiRNAnutrigenomicsPCRpomegranateRNASNPs

Identifiers

PMID29109097
PMCPMC6070330
OpenAlexW2767903886

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.