Evidence map›Paper›PMID 29108381›Full record

ArticleOncotarget2017

Long-term prognosis of Guillain-Barré syndrome not determined by treatment options?

Ying Wang, Wenjuan Lang, Yaqian Zhang, Xiaoyi Ma, Chunkui Zhou, Hong-Liang Zhang

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Patient Outcomes Among Medicare Beneficiaries With Guillain-Barré Syndrome.Journal of the peripheral nervous system : JPNS · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Exploring the experiences of having Guillain-Barré Syndrome: A qualitative interview study.Health expectations : an international journal of public participation in health care and health policy · 2020
    Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Ying WangDepartment of Neurology, The First Hospital of Jilin University, Changchun, China.
Wenjuan LangDepartment of Neurology, The First Hospital of Jilin University, Changchun, China.
Yaqian ZhangDepartment of Neurology, The First Hospital of Jilin University, Changchun, China.
Xiaoyi MaDepartment of Neurology, The Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, China.
Chunkui ZhouDepartment of Neurology, The First Hospital of Jilin University, Changchun, China.
Hong-Liang ZhangDepartment of Neurology, The First Hospital of Jilin University, Changchun, China.
First Hospital of Jilin University · CNJilin University · CNThe Affiliated Hospital to Changchun University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe long-term follow-up system for Guillain-Barré syndrome (GBS) is not well established worldwide. In our study, the preliminary data of the long-term prognosis of GBS are collected to explore the prognosis of GBS and the effect of intravenous immunoglobulin (IVIg) treatment.

methodsThe follow-up data of 186 patients with GBS admitted from 2003 to 2013 were collected in 2015

resultsThe mortality rates were 2.15%, 5.45% and 7.89% at discharge, 2-5 years and 6-10 years after disease, respectively. The GBS disability scale score improved dramatically from discharge to 2-12 years after the acute phase. The self-limitation, the spontaneous recovery of disease, occurred both at acute phase and 2-5 years after discharge. Comparisons between IVIg-treated patients and GBS patients who only received supportive care revealed no significant difference of long-term prognosis.

conclusionThe long-term prognosis of GBS appears not to be influenced by treatment options. The long-term improvement of IVIg treated-patients might be due to the self-limitation of GBS per se instead of the IVIg treatment.

Indexed as

Guillain-Barré syndromeintravenous immunoglobulinlong-term prognosispredictorsself-limitation

Identifiers

PMID29108381
PMCPMC5668114
OpenAlexW2753139013

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.