ArticleOncotarget2017
Neural correlates of childhood trauma with executive function in young healthy adults.
Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Neuropsychological Impact of Trauma-Related Mental Illnesses: A Systematic Review of Clinically Meaningful Results.Neuropsychology review · 2020Pooled it
- How Psychological Trauma Affects Cognitive Functions: A Systematic Review and Meta-Analysis.Clinical neuropsychiatry · 2026Article
- Neural Correlates of Mentalizing Altered in Childhood Trauma and Cocaine Use Disorder.Research square · 2026Article
- The impact of childhood trauma on short video addiction: psychological and morphological correlates.Scientific reports · 2025Article
- Differential gray matter correlates and machine learning prediction of abuse and internalizing psychopathology in adolescent females.Scientific reports · 2025Article
- Temporal-Posterior Alpha Power in Resting-State Electroencephalography as a Potential Marker of Complex Childhood Trauma in Institutionalized Adolescents.Brain sciences · 2024Article
- Exploring stress response's role in executive function impairments among adults with early adverse childhood experiences.Scientific reports · 2024Article
- Trauma and the default mode network: review and exploratory study.Frontiers in behavioral neuroscience · 2024Article
- Altered spontaneous brain activity in Down syndrome and its relation with cognitive outcome.Scientific reports · 2022Article
- Enduring effect of abuse: Childhood maltreatment links to altered theory of mind network among adults.Human brain mapping · 2022Article
- Where there's a will, there's a way? Strategies to reduce or abstain from alcohol use developed by Northern Plains American Indian women participating in a brief, alcohol-exposed pregnancy preconceptual intervention.Alcoholism, clinical and experimental research · 2021Article
- The heart of the matter: Developing the whole child through community resources and caregiver relationships.Development and psychopathology · 2021Article
- Behavioral processes and risk for problem substance use in adolescents.Pharmacology, biochemistry, and behavior · 2020Review
- The sense of self in the aftermath of trauma: lessons from the default mode network in posttraumatic stress disorder.European journal of psychotraumatology · 2020Article
- Structural and Resting-State Brain Alterations in Trauma-Exposed Firefighters: Preliminary Results.Taehan Yongsang Uihakhoe chi · 2020Article
- Interpersonal early life trauma is associated with increased cerebral perfusion and poorer memory performance in post-9/11 veterans.NeuroImage. Clinical · 2020Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to investigate the relationship among childhood trauma, executive impairments, and altered resting-state brain function in young healthy adults. Twenty four subjects with childhood trauma and 24 age- and gender-matched subjects without childhood trauma were recruited. Executive function was assessed by a series of validated test procedures. Localized brain activity was evaluated by fractional amplitude of low frequency fluctuation (fALFF) method and compared between two groups. Areas with altered fALFF were further selected as seeds in subsequent functional connectivity analysis. Correlations of fALFF and connectivity values with severity of childhood trauma and executive dysfunction were analyzed as well. Subjects with childhood trauma exhibited impaired executive function as assessed by Wisconsin Card Sorting Test and Stroop Color Word Test. Traumatic individuals also showed increased fALFF in the right precuneus and decreased fALFF in the right superior temporal gyrus. Significant correlations of specific childhood trauma severity with executive dysfunction and fALFF value in the right precuneus were found in the whole sample. In addition, individuals with childhood trauma also exhibited diminished precuneus-based connectivity in default mode network with left ventromedial prefrontal cortex, left orbitofrontal cortex, and right cerebellum. Decreased default mode network connectivity was also associated with childhood trauma severity and executive dysfunction. The present findings suggest that childhood trauma is associated with executive deficits and aberrant default mode network functions even in healthy adults. Moreover, this study demonstrates that executive dysfunction is related to disrupted default mode network connectivity.
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