ArticleOncotarget2017
Age-adjusted Charlson comorbidity index score as predictor of survival of patients with digestive system cancer who have undergone surgical resection.
Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Prognostic utility of the Charlson comorbidity index in pancreatic cancer: a systematic review and meta‑analysis.World journal of surgical oncology · 2026Pooled it
- Robotic versus laparoscopic pancreaticoduodenectomy: a propensity score matching analysis of Taiwan's national health insurance database.BMC surgery · 2026Article
- Development and validation of a competing risk nomogram for predicting PICC-related venous thrombosis in patients with gastrointestinal malignancies.Frontiers in oncology · 2026Article
- New Surgical Criteria for Intraductal Papillary Mucinous Neoplasm Based on the Age-Adjusted Charlson Comorbidity Index Values and Presence of Solid Component.Diagnostics (Basel, Switzerland) · 2024Article
- Novel multifactor predictive model for postoperative survival in gallbladder cancer: a multi-center study.World journal of surgical oncology · 2024Article
- Effectiveness and Safety of Endoscopic Submucosal Dissection for Colorectal Neoplasm in Patients with High Charlson Comorbidity Index Score: A HASID Multicenter Study.Journal of clinical medicine · 2023Article
- Comorbidity in limited disease small-cell lung cancer: Age-adjusted Charlson comorbidity index and its association with overall survival following chemoradiotherapy.Clinical and translational radiation oncology · 2023Article
- Article
- Comparison of survival times of advanced cancer patients with palliative care at home and in hospital.PloS one · 2023Article
- Comparison of Symptom Severity and Progression in Advanced Cancer Patients Among Different Care Settings: A Secondary Analysis.Palliative medicine reports · 2023Article
- Prognosis after curative resection for stage IA gastric cancer in elderly patients: endoscopic submucosal dissection versus surgery.Surgery today · 2022Article
- Emilia-Romagna Surgical Colorectal Cancer Audit (ESCA): a value-based healthcare retro-prospective study to measure and improve the quality of surgical care in colorectal cancer.International journal of colorectal disease · 2022Observational
- The impact of the age-adjusted Charlson comorbidity index as a prognostic factor for endoscopic papillectomy in ampullary tumors.Journal of gastroenterology · 2022Article
- The Age-Adjusted Charlson Comorbidity Index Predicts Prognosis in Elderly Cancer Patients.Cancer management and research · 2022Article
- Outcomes of Older Patients with Resectable Colorectal Liver Metastases Cancer (CRLM): Single Center Experience.Current oncology (Toronto, Ont.) · 2021Article
- Baseline anaemia increases locally advanced rectal cancer mortality in older patients undergoing preoperative chemoradiation.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Article
- Outcomes and adverse factors for endoscopic mucosal resection (EMR) of colorectal polyps in elderly patients.Frontline gastroenterology · 2021Article
- RoboticWorld journal of gastrointestinal surgery · 2020Article
- Reduced Opioid Prescription Practices and Duration of Stay after TAP Block for Laparoscopic Appendectomy.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2020Article
- Disease Severity and Cost in Adhesive Small Bowel Obstruction.World journal of surgery · 2019Article
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4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Comorbidities have considerable effects on survival outcomes. The primary objective of this retrospective study was to examine the association between age-adjusted Charlson comorbidity index (ACCI) score and postoperative in-hospital mortality in patients with digestive system cancer who have undergone surgical resection of their cancers. Using electronic hospitalization summary reports, we identified 315,464 patients who had undergone surgery for digestive system cancer in top-rank (Grade 3A) hospitals in China between 2013 and 2015. The Cox proportional hazard regression model was applied to evaluate the effect of ACCI score on postoperative mortality, with adjustments for sex, type of resection, anesthesia methods, and caseload of each healthcare institution. The postoperative in-hospital mortality rate in the study cohort was 1.2% (3,631/315,464). ACCI score had a positive graded association with the risk of postoperative in-hospital mortality for all cancer subtypes. The adjusted HRs for postoperative in-hospital mortality scores ≥ 6 for esophagus, stomach, colorectum, pancreas, and liver and gallbladder cancer were 2.05 (95% CI: 1.45-2.92), 2.00 (95% CI: 1.60-2.49), 2.54 (95% CI: 2.02-3.21), 2.58 (95% CI: 1.68-3.97), and 4.57 (95% CI: 3.37-6.20), respectively, compared to scores of 0-1. These findings suggested that a high ACCI score is an independent predictor of postoperative in-hospital mortality in Chinese patients with digestive system cancer who have undergone surgical resection.
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