Evidence map›Paper›PMID 29108265›Full record

ArticleOncotarget2017

Cellular inhibitor of apoptosis protein 2 promotes the epithelial-mesenchymal transition in triple-negative breast cancer cells through activation of the AKT signaling pathway.

Su Ji Jo, Pil-Gu Park, Hye-Ran Cha, Sung Gwe Ahn, Min Jung Kim, Hyemi Kim, Ja Seung Koo, Joon Jeong, Jeon Han Park, Seung Myung Dong and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. World journal of gastrointestinal oncology · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Su Ji JoDepartment of Microbiology and Immunology, Yonsei University College of Medicine, Seoul, Republic of Korea.
Pil-Gu ParkDepartment of Microbiology and Immunology, Yonsei University College of Medicine, Seoul, Republic of Korea.
Hye-Ran ChaDepartment of Microbiology and Immunology, Yonsei University College of Medicine, Seoul, Republic of Korea.
Sung Gwe AhnBreast Cancer Center, Department of Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
Min Jung KimDepartment of Microbiology and Immunology, Yonsei University College of Medicine, Seoul, Republic of Korea.
Hyemi KimDepartment of Microbiology and Immunology, Yonsei University College of Medicine, Seoul, Republic of Korea.
Ja Seung KooDepartment of Pathology, Yonsei University College of Medicine, Seoul, Republic of Korea.
Joon JeongBreast Cancer Center, Department of Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
Jeon Han ParkDepartment of Microbiology and Immunology, Yonsei University College of Medicine, Seoul, Republic of Korea.
Seung Myung DongResearch Institute, National Cancer Center, Goyang, Republic of Korea.
Jae Myun LeeDepartment of Microbiology and Immunology, Yonsei University College of Medicine, Seoul, Republic of Korea.
Yonsei University · KRGangnam Severance Hospital · KRInternational Vaccine Institute · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Triple-negative breast cancer (TNBC) represents approximately 10-17% of all breast cancers, and patients with TNBC show a poorer short-term prognosis than patients with other types of breast cancer. TNBCs also have a higher tendency for early distant metastasis and cancer recurrence due to induction of the epithelial-mesenchymal transition (EMT). Several recent reports have suggested that inhibitor of apoptosis (IAP) proteins function as regulators of the EMT. However, the roles of these proteins in TNBC are not clear. Accordingly, we investigated the roles of cIAP2 in TNBC. Among eight

Indexed as

AKT signaling pathwaycellular inhibitor of apoptosis protein 2epithelial-mesenchymal transitiontriple-negative breast cancer

Identifiers

PMID29108265
PMCPMC5667998
OpenAlexW2743520966

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.