Evidence map›Paper›PMID 29107762›Full record

SynthesisBehaviour research and therapy2018

Major depression prevention effects for a cognitive-behavioral adolescent indicated prevention group intervention across four trials.

Paul Rohde, Frédéric N Brière, Eric Stice

Open access · greenAbstract readMeta-Analysis
In one paragraph

Synthesis in Behaviour research and therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 26 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Nature-Based Meditation, Rumination and Mental Wellbeing.International journal of environmental research and public health · 2022
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Paul RohdeOregon Research Institute, Eugene, USA. Electronic address: paulr@ori.org.
Frédéric N BrièreUniversité de Montréal, Québec, Canada.
Eric SticeOregon Research Institute, Eugene, USA.
Oregon Research Institute · USUniversité de Montréal · CA

Funding

Effectiveness Trial of an Adolescent Depression Prevention ProgramR01MH080853 · NIMH · OREGON RESEARCH INSTITUTE · PI ROHDE, PAUL D · 2009 to 2013
$2.8M
Depression Prevention Program for High-Risk AdolescentsR01MH067183 · NIMH · UNIVERSITY OF TEXAS AUSTIN · PI STICE, ERIC M · 2004 to 2008
$1.5M
Neurobiological Bases of Economic Choice BehaviorR00MH080852 · NIMH · WASHINGTON UNIVERSITY · PI PADOA-SCHIOPPA, CAMILLO · 2008 to 2010
$717k
Neurobiological Bases of Economic Choice BehaviorK99MH080852 · NIMH · HARVARD MEDICAL SCHOOL · PI PADOA-SCHIOPPA, CAMILLO · 2007 to 2007
$87k
NIMH NIH HHS K99 MH080852NIMH NIH HHS R00 MH080852NIMH NIH HHS R01 MH067183NIMH NIH HHS R01 MH080853
6 · The paper itself

Abstract

Major depressive disorder (MDD) in young people is a leading cause of disability but most depressed youth are not treated, emphasizing the need for effective prevention. Our goal is to synthesize MDD onset prevention effects for the Blues Program, a brief cognitive-behavioral (CB) indicated prevention group, by merging data from four trials (three of which included CB bibliotherapy) and conducting an individual patient data (IPD) meta-analysis. Data were available from 766 high school/college students (M age = 16.4, SD = 2.3; 60% female, 64% White). CB group resulted in significantly lower MDD incidence rates relative to brochure control that persisted to 6-month follow-up; CB group also was associated with a lower 2-year MDD incidence rate relative to bibliotherapy but heterogeneity across trials was detected. Contrasts between bibliotherapy and brochure control were nonsignificant. For significant contrasts, the number needed to treat (NNT) by CB group to prevent one MDD onset relative to brochure or bibliotherapy ranged from 10 to 21. A brief CB group depression prevention intervention for at-risk adolescent is achieving meaningful effects compared to both active and minimal controls but outcomes need to be improved, perhaps by better screening or augmentations to produce more persistent intervention effects.

Indexed as

Cognitive Behavioral TherapyPrimary PreventionRandomized Controlled Trials as TopicAdolescentBibliotherapyFemaleHumansIncidenceMajor Depressive DisorderMalePsychotherapy, GroupYoung AdultAdolescentsBibliotherapyCognitive-behavioralGroup interventionMajor depressionPrevention

Identifiers

PMID29107762
PMCPMC5794620
OpenAlexW2766880584

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.