Evidence map›Paper›PMID 29107609›Full record

ReviewDevelopmental cognitive neuroscience2018

The utility of twins in developmental cognitive neuroscience research: How twins strengthen the ABCD research design.

William G Iacono, Andrew C Heath, John K Hewitt, Michael C Neale, Marie T Banich, Monica M Luciana, Pamela A Madden, Deanna M Barch, James M Bjork

Erratum issuedOpen access · goldAbstract readReview
In one paragraph

Review in Developmental cognitive neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 62 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 1 synthesis or guideline pooled it, 96 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. From adolescence to Alzheimer's: a neurodevelopmental lifespan model of cognitive vulnerability.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Review
  4. Article
  5. Article
  6. Mental health trajectory groups: Family income, neighborhood disadvantage, and role of the school environment.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2026
    Article
  7. Review
  8. Article
  9. Article
  10. Observational
  11. Article
  12. Article
  13. Article
  14. Article
  15. Depressive symptoms during the transition to adolescence: Left hippocampal volume as a marker of social context sensitivity.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Dissociation of Reliability, Heritability, and Predictivity in Coarse- and Fine-Scale Functional Connectomes during Development.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  20. Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

William G IaconoUniversity of Minnesota, United States. Electronic address: wiacono@umn.edu.
Andrew C HeathWashington University in St Louis, United States.
John K HewittUniversity of Colorado Boulder, United States.
Michael C NealeVirginia Commonwealth University, United States.
Marie T BanichUniversity of Colorado Boulder, United States.
Monica M LucianaUniversity of Minnesota, United States.
Pamela A MaddenWashington University in St Louis, United States.
Deanna M BarchWashington University in St Louis, United States.
James M BjorkVirginia Commonwealth University, United States.
Washington University in St. Louis · USUniversity of Minnesota System · USVirginia Commonwealth University · USUniversity of Colorado Boulder · USUniversity of Colorado System · US

Funding

ABCD-USA Consortium: Coordinating CenterU24DA041147 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SANDRA A BROWN, TERRY L. JERNIGAN · 2015 to 2026
$54.7M
ABCD-USA Consortium: Data Analysis, Informatics and Resource CenterU24DA041123 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ANDERS M DALE · 2015 to 2026
$51.5M
VALIDITY OF SUBTYPES OF ADHDP50HD027802 · NICHD · UNIVERSITY OF COLORADO AT BOULDER · PI ERIK G WILLCUTT · 1990 to 2026
$44.9M
Adolescent Substance Use Initiation: Disentangling neurocognitive risks from consequences using longitudinal and genetically-informed methodsU01DA041120 · NIDA · UNIVERSITY OF MINNESOTA · PI Monica Luciana, Sylia Wilson · 2015 to 2026
$34.5M
ABCD-USA Consortium: Research ProjectU01DA041089 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Joanna Jacobus, Susan F. Tapert · 2015 to 2026
$31.7M
ABCD-USA CONSORTIUM: RESEARCH PROJECTU01DA041048 · NIDA · CHILDREN'S HOSPITAL OF LOS ANGELES · PI Megan Marie Herting, ELIZABETH R SOWELL · 2015 to 2026
$28.7M
ABCD-USA Consortium: Research ProjectU01DA041106 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Mary M Heitzeg, Chandra Sekhar Sripada · 2015 to 2026
$24.9M
ABCD-USA Consortium: Research ProjectU01DA041148 · NIDA · OREGON HEALTH & SCIENCE UNIVERSITY · PI Damien A Fair, Rebekah S Huber · 2015 to 2026
$22.3M
ABCD-USA: NYC Research ProjectU01DA041174 · NIDA · YALE UNIVERSITY · PI Arielle Ryan Baskin-Sommers, Betty J Casey · 2015 to 2026
$19.7M
21/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT WUSTLU01DA051038 · NIDA · WASHINGTON UNIVERSITY · PI Deanna Barch, ANDREW C. HEATH · 2020 to 2026
$13.7M
ABCD-USA Consortium: Research ProjectU01DA041022 · NIDA · SRI INTERNATIONAL · PI Fiona C Baker, Eva M Muller-Oehring · 2015 to 2026
$13.4M
14/21 ABCD-USA Consortium: Research Project Site at CU BoulderU01DA051018 · NIDA · UNIVERSITY OF COLORADO · PI Marie T Banich, Naomi P. Friedman · 2020 to 2026
$11.4M
NICHD NIH HHS P50 HD027802NIDA NIH HHS U01 DA041022NIDA NIH HHS U01 DA041048NIDA NIH HHS U01 DA041089NIDA NIH HHS U01 DA041093NIDA NIH HHS U01 DA041106NIDA NIH HHS U01 DA041120NIDA NIH HHS U01 DA041148NIDA NIH HHS U01 DA041174NIDA NIH HHS U01 DA051018NIDA NIH HHS U01 DA051038NIDA NIH HHS U24 DA041123NIDA NIH HHS U24 DA041147
6 · The paper itself

Abstract

The ABCD twin study will elucidate the genetic and environmental contributions to a wide range of mental and physical health outcomes in children, including substance use, brain and behavioral development, and their interrelationship. Comparisons within and between monozygotic and dizygotic twin pairs, further powered by multiple assessments, provide information about genetic and environmental contributions to developmental associations, and enable stronger tests of causal hypotheses, than do comparisons involving unrelated children. Thus a sub-study of 800 pairs of same-sex twins was embedded within the overall Adolescent Brain and Cognitive Development (ABCD) design. The ABCD Twin Hub comprises four leading centers for twin research in Minnesota, Colorado, Virginia, and Missouri. Each site is enrolling 200 twin pairs, as well as singletons. The twins are recruited from registries of all twin births in each State during 2006-2008. Singletons at each site are recruited following the same school-based procedures as the rest of the ABCD study. This paper describes the background and rationale for the ABCD twin study, the ascertainment of twin pairs and implementation strategy at each site, and the details of the proposed analytic strategies to quantify genetic and environmental influences and test hypotheses critical to the aims of the ABCD study.

Indexed as

AdolescentAdolescent DevelopmentBrainChildCognitionCognitive NeuroscienceFemaleHumansMaleResearch DesignTwins, MonozygoticBrain functionBrain structureEnvironmentHeritabilitySubstance useTwins

Identifiers

PMID29107609
PMCPMC5847422
OpenAlexW2756017281

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.