Evidence map›Paper›PMID 29107569›Full record

Trial reportThe Journal of adolescent health : official publication of the Society for Adolescent Medicine2018

School Support as Structural HIV Prevention for Adolescent Orphans in Western Kenya.

Hyunsan Cho, Isabella Mbai, Winnie Kavulani Luseno, Marcia Hobbs, Carolyn Halpern, Denise Dion Hallfors

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
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  4. Process Evaluation of a Clinical Trial to Test School Support as HIV Prevention Among Orphaned Adolescents in Western Kenya.Prevention science : the official journal of the Society for Prevention Research · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Hyunsan ChoThe Pacific Institute for Research and Evaluation, Chapel Hill, North Carolina. Electronic address: cho@pire.org.
Isabella MbaiSchool of Nursing, Moi University, Eldoret, Kenya.
Winnie Kavulani LusenoThe Pacific Institute for Research and Evaluation, Chapel Hill, North Carolina.
Marcia HobbsDepartment of Medicine, Microbiology & Immunology and Allied Health Sciences, University of North Carolina, Chapel Hill, North Carolina.
Carolyn HalpernDepartment of Maternal and Child Health, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina.
Denise Dion HallforsThe Pacific Institute for Research and Evaluation, Chapel Hill, North Carolina.
Pacific Institute For Research and Evaluation · USUniversity of North Carolina at Chapel Hill · USMoi University · KE

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
Research Services CoreP2CHD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KAREN B GUZZO · 2015 to 2026
$9.6M
School Support as Structural HIV Prevention for Adolescent Orphans in Western KenR01MH092215 · NIMH · PACIFIC INSTITUTE FOR RES AND EVALUATION · PI CHO, HYUNSAN · 2011 to 2015
$3.2M
NIAID NIH HHS P30 AI050410NICHD NIH HHS P2C HD050924NIMH NIH HHS R01 MH092215
6 · The paper itself

Abstract

purposeUsing a clustered randomized controlled trial design, we evaluated whether support to keep Kenyan orphaned adolescents in school reduces the risk of HIV infection.

methodsParticipants included 835 orphaned boys and girls in grades 7 and 8 (mean age at the baseline = 15 years) in western Kenya. Primary schools (N = 26) were randomized to the study condition. Intervention participants received school uniforms, payment of tuition when they transitioned into high school, and nurse visits to monitor school absenteeism and provide assistance to stay in school. Annual surveys were conducted from 2011 through 2014, and HIV and herpes simplex virus 2 (HSV-2) biomarker data were collected at the baseline and the end line. Data were analyzed using survey logistic regression or generalized estimating equations controlling for age, gender, and socioeconomic status.

resultsIntervention and control groups were equivalent at the baseline and did not differ on new HIV or HSV-2 incidence at the end line. The school support intervention increased school retention but had few HIV-related effects, except increased circumcision among male participants and reduced likelihood of transactional sex.

conclusionsDespite a strong study design, we found no relative reduction in HIV or HSV-2 infection after 3 years of intervention implementation. New incidence of HIV was lower than expected in this region among youth whose average age at end line was 18 years (range = 14-23). Although support for secondary school promises many benefits for vulnerable youth, our study adds to the growing body of research showing weak evidence for its effectiveness as an HIV prevention.

Indexed as

Child, OrphanedAdolescentFemaleHIV InfectionsHumansKenyaMaleSchoolsSexual BehaviorSocioeconomic FactorsHIVKenyaOrphansSchool support

Identifiers

PMID29107569
PMCPMC5742035
OpenAlexW2766561484

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.