Evidence map›Paper›PMID 29106774›Full record

ArticleJournal of clinical hypertension (Greenwich, Conn.)2018

Do thiazide diuretics reduce central systolic blood pressure in hypertension?

Lara B T Yugar, Beatriz Moreno, Heitor Moreno, José F Vilela-Martin, Juan C Yugar-Toledo

Registry-linked trialOpen access · bronzeAbstract readEditorial
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical hypertension (Greenwich, Conn.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03923933 (Chlortalidone and Bumetanide in Advanced Chronic Kidney Disease), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03923933 phase2completednot on this mapstarted 2019, after this paper: background citation

Chlortalidone and Bumetanide in Advanced Chronic Kidney Disease: HEBE-CKD Trial

TypeinterventionalSponsorHospital General de México Dr. Eduardo LiceagaRan2019 to 2019Enrolled34ConditionsRenal Insufficiency, ChronicArmsChlorthalidone, Bumetanide
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Lara B T YugarBotucatu School of Medicine/São Paulo State University (FMB/UNESP), Botucatu, Brazil.
Beatriz MorenoSection of Cardiovascular Pharmacology and Hypertension, Department of Pharmacology, Faculty of Medical Sciences, State University of Campinas (UNICAMP), Campinas, Brazil.
Heitor MorenoSection of Cardiovascular Pharmacology and Hypertension, Department of Pharmacology, Faculty of Medical Sciences, State University of Campinas (UNICAMP), Campinas, Brazil.ORCID 0000-0001-6330-697X
José F Vilela-MartinDepartment of Internal Medicine, Hypertension Clinic, State Medical School of São José do Rio Preto (FAMERP), São Paulo, Brazil.
Juan C Yugar-ToledoDepartment of Internal Medicine, Hypertension Clinic, State Medical School of São José do Rio Preto (FAMERP), São Paulo, Brazil.ORCID 0000-0001-6583-6536
Faculdade de Medicina de São José do Rio Preto · BRUniversidade Estadual de Campinas (UNICAMP) · BRUniversidade Estadual Paulista (Unesp) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HypertensionAmilorideAntihypertensive AgentsArterial PressureBlood PressureChlorthalidoneDiureticsDrug CombinationsHumansTreatment OutcomeVascular StiffnessAmilorideAntihypertensive AgentsChlorthalidoneDiureticsDrug Combinationsamiloridecentral blood pressurechlorthalidonelosartanstage 1 hypertension

Identifiers

PMID29106774
PMCPMC8031112
OpenAlexW2767784624

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.