Evidence map›Paper›PMID 29106550›Full record

ArticleNucleic acids research2018

The OMA orthology database in 2018: retrieving evolutionary relationships among all domains of life through richer web and programmatic interfaces.

Adrian M Altenhoff, Natasha M Glover, Clément-Marie Train, Klara Kaleb, Alex Warwick Vesztrocy, David Dylus, Tarcisio M de Farias, Karina Zile, Charles Stevenson, Jiao Long and 3 more

Abstract read
In one paragraph

Article in Nucleic acids research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 135 papers.

0numbers the graph read from it
0cells of the map it votes in
135citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

135 citing papers in PubMed.

  1. Trial
  2. Article
  3. Assessing the Evolutionary Conservation of Protein Disulfide Bonds.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  4. Article
  5. Article
  6. Article
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  8. Article
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  11. On the Unknown Proteins of Eukaryotic Proteomes.Journal of molecular evolution · 2023
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
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  18. Article
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  20. Intrinsic protein disorder uncouples affinity from binding specificity.Protein science : a publication of the Protein Society · 2022
    Article

75 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Adrian M AltenhoffSIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland.
Natasha M GloverSIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland.
Clément-Marie TrainSIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland.
Klara KalebDept. of Genetics, Evolution & Environment, University College London, Gower St, London WC1E 6BT, UK.
Alex Warwick VesztrocySIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland.
David DylusSIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland.
Tarcisio M de FariasSIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland.
Karina ZileSIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland.
Charles StevensonDept. of Genetics, Evolution & Environment, University College London, Gower St, London WC1E 6BT, UK.
Jiao LongBayer Crop Science NV, Technologiepark 38, 9052 Gent, Belgium.
Henning RedestigBayer Crop Science NV, Technologiepark 38, 9052 Gent, Belgium.
Gaston H GonnetSIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland.
Christophe DessimozSIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland.

Funding

Biotechnology and Biological Sciences Research Council BB/L018241/1Biotechnology and Biological Sciences Research Council BB/M009513/1
6 · The paper itself

Abstract

The Orthologous Matrix (OMA) is a leading resource to relate genes across many species from all of life. In this update paper, we review the recent algorithmic improvements in the OMA pipeline, describe increases in species coverage (particularly in plants and early-branching eukaryotes) and introduce several new features in the OMA web browser. Notable improvements include: (i) a scalable, interactive viewer for hierarchical orthologous groups; (ii) protein domain annotations and domain-based links between orthologous groups; (iii) functionality to retrieve phylogenetic marker genes for a subset of species of interest; (iv) a new synteny dot plot viewer; and (v) an overhaul of the programmatic access (REST API and semantic web), which will facilitate incorporation of OMA analyses in computational pipelines and integration with other bioinformatic resources. OMA can be freely accessed at https://omabrowser.org.

Indexed as

Biological EvolutionDatabases, GeneticGenomeMolecular Sequence AnnotationSyntenyAlgorithmsAnimalsArchaeaBacteriaComputational BiologyFungiGene OntologyHumansInternetPhylogenyPlantsProteins

Identifiers

PMID29106550
PMCPMC5753216

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.