Evidence map›Paper›PMID 29106375›Full record

ArticleeLife2017

Genetic and neuronal regulation of sleep by neuropeptide VF.

Daniel A Lee, Andrey Andreev, Thai V Truong, Audrey Chen, Andrew J Hill, Grigorios Oikonomou, Uyen Pham, Young K Hong, Steven Tran, Laura Glass and 4 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 79 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Daniel A LeeDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.ORCID http://orcid.org/0000-0001-7411-2740
Andrey AndreevDepartment of Bioengineering, University of Southern California, Los Angeles, United States.
Thai V TruongTranslational Imaging Center, University of Southern California, Los Angeles, United States.
Audrey ChenDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.
Andrew J HillDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.
Grigorios OikonomouDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.
Uyen PhamDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.
Young K HongDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.
Steven TranDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.ORCID http://orcid.org/0000-0001-8515-8250
Laura GlassDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.
Viveca SapinDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.
Jae EngleDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.
Scott E FraserDepartment of Bioengineering, University of Southern California, Los Angeles, United States.
David A ProberDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.ORCID http://orcid.org/0000-0002-7371-4675
California Institute of Technology · USUniversity of Southern California · US

Funding

Dynamic mapping of the complete synaptome using recombinant probesR01MH107238 · NIMH · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ARNOLD, DONALD B, FRASER, SCOTT E · 2014 to 2018
$9.7M
Neuropeptidergic Regulation of Zebrafish SleepR01NS070911 · NINDS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI PROBER, DAVID AARON · 2011 to 2020
$3.5M
Role of Prokineticin 2 in Regulating Sleep in ZebrafishR01NS095824 · NINDS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI PROBER, DAVID AARON · 2017 to 2021
$1.8M
Circadian Regulation of Zebrafish Sleep by MelatoninR01NS101665 · NINDS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI PROBER, DAVID AARON · 2017 to 2020
$1.4M
Regulation of Zebrafish Sleep by Neuromedin UR01NS101158 · NINDS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI PROBER, DAVID AARON · 2017 to 2020
$1.4M
Mechanisms of Sleep Regulation by EGFR-Mediated Neural and Molecular CircuitsK99NS097683 · NINDS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI LEE, DANIEL ALLEN · 2016 to 2017
$182k
Regulation of Sleep and Circadian Behaviors by TGF-alpha SignalingF32NS084769 · NINDS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI LEE, DANIEL ALLEN · 2013 to 2015
$159k
Hypocretin and Locus Ceruleus Interactions in Zebrafish Development and BehaviorF32NS082010 · NINDS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI OIKONOMOU, GRIGORIOS · 2012 to 2015
$159k
NIMH NIH HHS R01 MH107238NINDS NIH HHS F32 NS082010NINDS NIH HHS F32 NS084769NINDS NIH HHS K99 NS097683NINDS NIH HHS R01 NS070911NINDS NIH HHS R01 NS095824NINDS NIH HHS R01 NS101158NINDS NIH HHS R01 NS101665
6 · The paper itself

Abstract

Sleep is an essential and phylogenetically conserved behavioral state, but it remains unclear to what extent genes identified in invertebrates also regulate vertebrate sleep. RFamide-related neuropeptides have been shown to promote invertebrate sleep, and here we report that the vertebrate hypothalamic RFamide neuropeptide VF (NPVF) regulates sleep in the zebrafish, a diurnal vertebrate. We found that NPVF signaling and

Indexed as

Gene Expression RegulationSleepAnimalsNeuronsNeuropeptidesSignal TransductionZebrafishNeuropeptidesneuropeptide VFbehaviorgeneticshypothalamusneuropeptide VFneuroscienceRFamide neuropeptidesleepzebrafish

Identifiers

PMID29106375
PMCPMC5705210
OpenAlexW2767264485

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.