Evidence map›Paper›PMID 29106357›Full record

ArticleBlood transfusion = Trasfusione del sangue2018

Position Paper on laboratory testing for patients on direct oral anticoagulants. A Consensus Document from the SISET, FCSA, SIBioC and SIPMeL.

Armando Tripodi, Walter Ageno, Marcello Ciaccio, Cristina Legnani, Giuseppe Lippi, Cesare Manotti, Rossella Marcucci, Marco Moia, Benedetto Morelli, Daniela Poli and 2 more

Registry-linked trialAbstract readConsensus Statement
In one paragraph

Article in Blood transfusion = Trasfusione del sangue, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04271293 (anticOagulanti oRali in pazIenti fraGili Con gAstrostoMia endoscopIca Percutanea e fIbrillazione Atriale), which is not on this map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04271293 completednot on this mapstarted 2020, after this paper: background citation

anticOagulanti oRali in pazIenti fraGili Con gAstrostoMia endoscopIca Percutanea e fIbrillazione Atriale

TypeobservationalSponsorFondazione Policlinico Universitario Agostino Gemelli IRCCSRan2020 to 2021Enrolled12ConditionsAtrial FibrillationArmsEdoxaban
3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

  1. Article
  2. Article
  3. Is Laboratory Monitoring Useful in DOAC Management?Mediterranean journal of hematology and infectious diseases · 2025
    Article
  4. Direct oral anticoagulants measurement: when is it necessary?Blood transfusion = Trasfusione del sangue · 2025
    Article
  5. Article
  6. Post-extraction bleeding in patients on direct oral anticoagulants.Journal of the Korean Association of Oral and Maxillofacial Surgeons · 2024
    Article
  7. Review
  8. How the Hemostasis Laboratory Can Help Clinicians to Manage Patients on Oral Anticoagulants.Mediterranean journal of hematology and infectious diseases · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. The Influence of ABCB1 (rs1045642 and rs4148738) Gene Polymorphisms on Rivaroxaban Pharmacokinetics in Patients Aged 80 Years and Older with Nonvalvular Atrial Fibrillation.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Armando Tripodi"Angelo Bianchi Bonomi" Haemophilia and Thrombosis Centre, Department of Clinical Sciences and Community Health, University of Milan and IRCCS Maggiore Hospital, Milan, Italy.
Walter AgenoResearch Centre on Thromboembolic Diseases and Antithrombotic Therapies, Department of Clinical and Experimental Medicine, University of Insubria, Varese, Italy.
Marcello CiaccioSection of Clinical Biochemistry and Clinical Molecular Medicine, Department of Biopathology and Medical Biotechnology, University of Palermo, Palermo, Italy.
Cristina LegnaniAngiology and Blood Coagulation, University Hospital of Bologna, Bologna, Italy.
Giuseppe LippiSection of Clinical Biochemistry, University of Verona, Verona, Italy.
Cesare ManottiHaemostasis Centre, Fidenza-Vaio Hospital, Fidenza, Italy.
Rossella MarcucciDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Marco Moia"Angelo Bianchi Bonomi" Haemophilia and Thrombosis Centre, Department of Clinical Sciences and Community Health, University of Milan and IRCCS Maggiore Hospital, Milan, Italy.
Benedetto MorelliSIBioC Haemostasis and Thrombosis Study Group, Milan, Italy.
Daniela PoliThrombosis Centre, "Careggi" University Hospital, Florence, Italy.
Agostino SteffanTranslational Research Department, Cancer Referral Centre, Aviano, Italy.
Sophie TestaDepartment of Laboratory Medicine, Haemostasis and Thrombosis Centre, Hospital Institutes, Cremona, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although direct oral anticoagulants (DOAC) do not require dose-adjustment on the basis of laboratory test results, the measurement of their anticoagulant effect is useful in special situations. This position paper issued by the Italian Scientific Societies that are mainly involved in the management of patients on DOAC is aimed at providing guidance to care-givers on which tests should be used and the situations in which testing is useful. The guidance is based on the data from the literature so far available and/or on consensus among experts.

Indexed as

Administration, OralAnticoagulantsDrug MonitoringHumansItalySocieties, ScientificAnticoagulants

Identifiers

PMID29106357
PMCPMC6125231

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.