Evidence map›Paper›PMID 29105871›Full record

Trial reportAddiction (Abingdon, England)2018

Cost-effectiveness of personal tailored risk information and taster sessions to increase the uptake of the NHS stop smoking services: the Start2quit randomized controlled trial.

Qi Wu, Hazel Gilbert, Irwin Nazareth, Stephen Sutton, Richard Morris, Irene Petersen, Simon Galton, Steve Parrott

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Addiction (Abingdon, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Strategies to improve smoking cessation rates in primary care.The Cochrane database of systematic reviews · 2021
    Pooled it
  4. Pooled it
  5. Trial
  6. Article
  7. Article
  8. Observational
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Qi WuDepartment of Health Sciences, University of York, York, UK.ORCID 0000-0002-8281-7799
Hazel GilbertResearch Department of Primary Care and Population Health, UCL, London, UK.
Irwin NazarethResearch Department of Primary Care and Population Health, UCL, London, UK.
Stephen SuttonInstitute of Public Health, University of Cambridge, Cambridge, UK.
Richard MorrisResearch Department of Primary Care and Population Health, UCL, London, UK.
Irene PetersenResearch Department of Primary Care and Population Health, UCL, London, UK.
Simon GaltonSmokefree Camden (Public Health), NHS Camden, London, UK.
Steve ParrottDepartment of Health Sciences, University of York, York, UK.

Funding

Department of Health 08/58/02Medical Research Council MR/K023195/1
6 · The paper itself

Abstract

aimsTo assess the cost-effectiveness of a two-component intervention designed to increase attendance at the NHS Stop Smoking Services (SSSs) in England.

designCost-effectiveness analysis alongside a randomized controlled trial (Start2quit).

settingNHS SSS and general practices in England.

participantsThe study comprised 4384 smokers aged 16 years or more identified from medical records in 99 participating practices, who were motivated to quit and had not attended the SSS in the previous 12 months. INTERVENTION AND COMPARATOR: Intervention was a personalized and tailored letter sent from the general practitioner (GP) and a personal invitation and appointment to attend a taster session providing information about SSS. Control was a standard generic letter from the GP advertising SSS and asking smokers to contact the service to make an appointment. MEASUREMENTS: Costs measured from an NHS/personal social services perspective, estimated health gains in quality-adjusted life-years (QALYs) measured with EQ-5D and incremental cost per QALY gained during both 6 months and a life-time horizon.

findingsDuring the trial period, the adjusted mean difference in costs was £92 [95% confidence interval (CI) = -£32 to -£216) and the adjusted mean difference in QALY gains was 0.002 (95% CI = -0.001 to 0.004). This generates an incremental cost per QALY gained of £59 401. The probability that the tailored letter and taster session is more cost-effective than the generic letter at 6 months is never above 50%. In contrast, the discounted life-time health-care cost was lower in the intervention group, while the life-time QALY gains were significantly higher. The probability that the intervention is more cost-effective is more than 83% using a £20 000-30 000 per QALY-gained decision-making threshold.

conclusionsAn intervention designed to increase attendance at the NHS Stop Smoking Services (tailored letter and taster session in the services) appears less likely to be cost-effective than a generic letter in the short term, but is likely to become more cost-effective than the generic letter during the long term.

Indexed as

Patient SelectionSmoking CessationCost-Benefit AnalysisEnglandGeneral PractitionersHumansPatient Education as TopicQuality-Adjusted Life YearsRiskSmokingState MedicineUnited KingdomCost-effectivenesspersonal tailored risk informationrandomized controlled trialsmoking cessationstop smoking servicesuptake of service

Identifiers

PMID29105871
PMCPMC5873401

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.