Evidence map›Paper›PMID 29105795›Full record

ArticleThe Prostate2018

FOXP3

Sabina Davidsson, Ove Andren, Anna-Lena Ohlson, Jessica Carlsson, Swen-Olof Andersson, Francesca Giunchi, Jennifer R Rider, Michelangelo Fiorentino

Open access · hybridAbstract read
In one paragraph

Article in The Prostate, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 56 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. CACYBP knockdown inhibits progression of prostate cancer via p53.Journal of cancer research and clinical oncology · 2023
    Article
  8. Article
  9. The Role ofMicroorganisms · 2022
    Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Hormonal Therapy for Prostate Cancer.Endocrine reviews · 2021
    Review
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Sabina DavidssonDepartment of Urology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.ORCID http://orcid.org/0000-0002-2850-6009
Ove AndrenDepartment of Urology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
Anna-Lena OhlsonDepartment of Laboratory Medicine, Pathology, University Hospital Örebro, Örebro, Sweden.
Jessica CarlssonDepartment of Urology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
Swen-Olof AnderssonDepartment of Urology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
Francesca GiunchiDepartment of Hematology-Oncology, Molecular Pathology Laboratory, Addarii Institute of Oncology, University of Bologna, Bologna, Italy.
Jennifer R RiderDepartment of Epidemiology, Boston University School of Public Health, Boston, Massachusetts.
Michelangelo FiorentinoDepartment of Hematology-Oncology, Molecular Pathology Laboratory, Addarii Institute of Oncology, University of Bologna, Bologna, Italy.
Örebro University · SEUniversity of Bologna · ITBoston University · USÖrebro University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe tumor promoting or counteracting effects of the immune response to cancer development are thought to be mediated to some extent by the infiltration of regulatory T cells (T

methodsStudy subjects were 102 men consecutively diagnosed with localized prostate cancer undergoing radical prostatectomy and 38 men diagnosed with bladder cancer undergoing cystoprostatectomy without prostate cancer at the pathological examination. Whole mount sections from all patients were evaluated for the epithelial and stromal expression of CD4

resultsIn men with prostate cancer, similarly high numbers of stromal CD4

conclusionsOur results may suggest a possible pathway through which PAH develops directly into prostate cancer in the presence of CD4

Indexed as

Forkhead Transcription FactorsHumansMaleProstateProstatectomyProstatic Intraepithelial NeoplasiaProstatic NeoplasmsT-Lymphocytes, RegulatoryUrinary Bladder NeoplasmsForkhead Transcription FactorsFOXP3 protein, humanCD4+FOXP3+ TregsLag-3+ Tregsprostate carcinoma

Identifiers

PMID29105795
PMCPMC5725695
OpenAlexW2767512341

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.