Evidence map›Paper›PMID 29105545›Full record

ArticlePrion2017

Electron microscopic and confocal laser microscopy analysis of amyloid plaques in chronic wasting disease transmitted to transgenic mice.

Beata Sikorska, Agata Gajos, Andrzej Bogucki, Emil Zielonka, Christina Sigurdson, Pawel P Liberski

Open access · goldAbstract read
In one paragraph

Article in Prion, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 85% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Beata Sikorskaa Department of Molecular Pathology and Neuropathology , Medical University of Lodz , Kosciuszki 4 st, Lodz , Poland.
Agata Gajosb Department of Extrapyramidal Diseases , Medical University of Lodz , Kosciuszki 4 st, Lodz , Poland.
Andrzej Boguckib Department of Extrapyramidal Diseases , Medical University of Lodz , Kosciuszki 4 st, Lodz , Poland.
Emil Zielonkaa Department of Molecular Pathology and Neuropathology , Medical University of Lodz , Kosciuszki 4 st, Lodz , Poland.
Christina Sigurdsonc Center for Veterinary Sciences and Comparative Medicine , University of California , San Diego , United States of America.
Pawel P Liberskia Department of Molecular Pathology and Neuropathology , Medical University of Lodz , Kosciuszki 4 st, Lodz , Poland.
Medical University of Lodz · PLUniversity of California, San Diego · US

Funding

VIRUS-INDUCED BRAIN PATHOLOGYP50AG005131 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BREWER, JAMES B · 1985 to 2018
$55.4M
Mechanisms of Prion Aggregation and Species BarriersR01NS069566 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ESKO, JEFFREY D, RAVITS, JOHN · 2011 to 2025
$5.7M
Mechanisms of Prion SpreadR01NS076896 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SIGURDSON, CHRISTINA · 2012 to 2021
$3.4M
NIA NIH HHS P50 AG005131NINDS NIH HHS R01 NS069566NINDS NIH HHS R01 NS076896
6 · The paper itself

Abstract

We report here on the ultrastructure of amyloid plaques in chronic wasting disease (CWD) transmitted to Tg20 transgenic mice overexpressing prion protein (PrP

Indexed as

AnimalsBrain StemCorpus CallosumFluorescent Antibody TechniqueHumansImmunohistochemistryMiceMice, TransgenicMicroscopy, ConfocalMicroscopy, ElectronPlaque, AmyloidPrion DiseasesWasting Disease, Chronicamyloid plaques – microglial cellsChronic wasting disease – prion diseases

Identifiers

PMID29105545
PMCPMC5786356
OpenAlexW2779870213

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.