Evidence map›Paper›PMID 29104965›Full record

ArticleJournal of stem cell and regenerative biology2017

Immunomodulation by Mesenchymal Stromal Cells and Their Clinical Applications.

Joaquin Cagliani, Daniel Grande, Ernesto P Molmenti, Edmund J Miller, Horacio L R Rilo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of stem cell and regenerative biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  17. Cryobanking European Mink (International journal of molecular sciences · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joaquin CaglianiThe Feinstein Institute for Medical Research, Center for Heart and Lungs, Northwell Health System, Manhasset, N Y, USA.
Daniel GrandeThe Feinstein Institute for Medical Research, Orthopedic Research Laboratory, Northwell Health System, Manhasset, N Y, USA.
Ernesto P MolmentiTransplantation of Surgery, Department of Surgery, Northwell Health System, Manhasset, NY, USA.
Edmund J MillerThe Feinstein Institute for Medical Research, Center for Heart and Lungs, Northwell Health System, Manhasset, N Y, USA.
Horacio L R RiloPancreas Disease Center, Department of Surgery, Northwell Health System, Manhasset, NY, USA.

Funding

MIF-Thyroxine Interactions in the Pathogenesis of Pulmonary Arterial HypertensionR01HL111469 · NHLBI · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI MILLER, EDMUND J · 2013 to 2016
$1.7M
NHLBI NIH HHS R01 HL111469
6 · The paper itself

Abstract

Mesenchymal stromal cells (MSCs) are multipotent progenitor cells that can be isolated and expanded from various sources. MSCs modulate the function of immune cells, including T and B lymphocytes, dendritic cells, and natural killer cells. An understanding of the interaction between MSCs and the inflammatory microenvironment will provide critical information in revealing the precise

Indexed as

Animal studiesCell therapyClinical trialsImmunomodulationImmunosuppressionMesenchymal stromal cells

Identifiers

PMID29104965
PMCPMC5667922

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.