Evidence map›Paper›PMID 29104953›Full record

ArticleACS omega2017

Exploring the Multiligand Binding Specificity of Saposin B Reveals Two Binding Sites.

Jay Tinklepaugh, Britannia M Smith, Etta Hanlon, Chloe Zubieta, Fadi Bou-Abdallah, Robert P Doyle

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Human Saposin B Ligand Binding and Presentation to α-Galactosidase A.bioRxiv : the preprint server for biology · 2024
    Article
  3. New Insights on the Uptake and Trafficking of Coenzyme Q.Antioxidants (Basel, Switzerland) · 2023
    Review
  4. Prosaposin mediates inflammation in atherosclerosis.Science translational medicine · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Jay TinklepaughDepartment of Chemistry, Syracuse University, 111 College Place, Syracuse, New York 13244, United States.
Britannia M SmithDepartment of Chemistry, State University of New York at Potsdam, Potsdam, New York 13676, United States.
Etta HanlonDepartment of Chemistry, Syracuse University, 111 College Place, Syracuse, New York 13244, United States.
Chloe ZubietaLaboratoire de Physiologie Cellulaire & Végétale, iRTSV, UMR 5168, CNRS/CEA/INRA/Univ. Grenoble Alpes, Grenoble 38054, France.
Fadi Bou-AbdallahDepartment of Chemistry, State University of New York at Potsdam, Potsdam, New York 13676, United States.
Robert P DoyleDepartment of Chemistry, Syracuse University, 111 College Place, Syracuse, New York 13244, United States.
State University of New York at Potsdam · USSyracuse University · USCentre National de la Recherche Scientifique · FRSUNY Upstate Medical University · US

Funding

Heteropolymer Ferritins Structure-Function StudiesR15GM104879 · NIGMS · STATE UNIVERSITY OF NEW YORK AT POTSDAM · PI BOU-ABDALLAH, FADI · 2015 to 2019
$675k
NIGMS NIH HHS R15 GM104879
6 · The paper itself

Abstract

Saposin B (SapB) is a human lysosomal protein, critical for the degradation of

Identifiers

PMID29104953
PMCPMC5664142
OpenAlexW2766894179

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.