Evidence map›Paper›PMID 29104861›Full record

ArticleWorld journal of transplantation2017

Graft loss among renal-transplant recipients with early reduction of immunosuppression for BK viremia.

Marwan M Azar, Roland Assi, Aziz K Valika, David B Banach, Isaac E Hall, Marie-Louise Landry, Maricar F Malinis

Open access · bronzeAbstract read
In one paragraph

Article in World journal of transplantation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Risk Prediction and Management of BKPyV-DNAemia in Kidney Transplant Recipients: A Multicenter Analysis of Immunosuppressive Strategies.Transplant international : official journal of the European Society for Organ Transplantation · 2025
    Article
  2. Article
  3. Acute Kidney Injury and BK Polyomavirus in Urine Sediment Cells.International journal of molecular sciences · 2023
    Article
  4. Immunosuppressive Agents and Infectious Risk in Transplantation: Managing the "Net State of Immunosuppression".Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Marwan M AzarDepartment of Pathology, Section of Microbiology, Massachusetts General Hospital, Boston, MA 02145, United States.
Roland AssiDepartment of Surgery, Yale University School of Medicine, New Haven, CT 06510, United States.
Aziz K ValikaAdventist Health Partners, Chicago, IL 60521, United States.
David B BanachDivision of Infectious Diseases, University of Connecticut School of Medicine, Farmington, CT 06032, United States.
Isaac E HallDivision of Hypertension and Nephrology, University of Utah School of Medicine, Dalt Lake City, UT 84132, United States.
Marie-Louise LandryDepartment of Laboratory Medicine, Yale University School of Medicine, New Haven, CT 06510, United States.
Maricar F MalinisSection of Infectious Diseases, Yale School of Medicine, New Haven, CT 06510, United States.
Yale University · USUniversity of Connecticut · USMassachusetts General Hospital · USUniversity of Utah · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

aimTo review the incidence of graft loss and acute rejection among renal transplant recipients with early reduction of immunosuppression for BK viremia.

methodsWe performed a retrospective analysis of consecutive

resultsAmong 319 kidney transplant recipients, the median age was 53 years (range 19-83), 65.8% were male, and 58.9% were white. Biopsy-proven acute rejection was found in 18.5% within 0-168 wk. Death-censored graft loss occurred in 5.3% (

conclusionInstituting an early reduction of immunosuppression, in the absence of adjunctive antivirals, is effective at preventing PyVAN and may be associated with a lower incidence of graft-loss without a reciprocal increase in the incidence of acute rejection.

Indexed as

BK virusGraft lossPreventionPyVANRenal transplantScreening

Identifiers

PMID29104861
PMCPMC5661124
OpenAlexW2765395404

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.