Evidence map›Paper›PMID 29104849›Full record

ReviewAllergo journal international2017

Current concepts in eosinophilic esophagitis.

Dagmar Simon, Alex Straumann, Alain M Schoepfer, Hans-Uwe Simon

Open access · hybridAbstract readReview
In one paragraph

Review in Allergo journal international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Dagmar SimonDepartment of Dermatology, Bern University Hospital, Inselspital, University of Bern, 3010 Bern, Switzerland.
Alex StraumannSwiss EoE Study Group, Olten, Switzerland.
Alain M SchoepferDepartment of Gastroenterology and Hepatology, Lausanne University Hospital CHUV, Lausanne, Switzerland.
Hans-Uwe SimonInstitute of Pharmacology, University of Bern, 3010 Bern, Switzerland.
University Hospital of Bern · CHUniversity of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEosinophilic esophagitis (EoE) is a disease entity first described in the 1990s, but showing an increasing incidence that is characterized clinically by esophageal dysfunction and histologically by a striking eosinophil infiltration.

methodsThis article discusses new aspects of the pathogenesis, symptoms, diagnosis, and treatment of EoE.

resultsEoE affects both children and adults and is frequently associated with atopic disease and IgE sensitization. Barrier dysfunction and T‑helper 2 inflammation are considered to be pathogenetically important factors. Recently, a proton pump inhibitor (PPI)-sensitive EoE subtype as well as an EoE-like disorder have been described.

conclusionResearch in recent years has contributed to a better understanding of the disease spectrum and pathogenesis of EoE, including genetic dispositions, thereby laying the foundation for innovative treatment approaches.

Indexed as

Barrier dysfunctionDietEosinophilic esophagitisEosinophilsT‑helper 2 inflammation

Identifiers

PMID29104849
PMCPMC5660132
OpenAlexW2756448133

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.