Evidence map›Paper›PMID 29104727›Full record

ArticleOxidative medicine and cellular longevity2017

Comparative Analysis of AGE and RAGE Levels in Human Somatic and Embryonic Stem Cells under H

Maria Barandalla, Elisa Haucke, Bernd Fischer, Alexander Navarrete Santos, Silvia Colleoni, Cesare Galli, Anne Navarrete Santos, Giovanna Lazzari

Open access · hybridAbstract readComparative Study
In one paragraph

Article in Oxidative medicine and cellular longevity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Role of NF-κB signaling pathway in HIn vitro cellular & developmental biology. Animal · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Maria BarandallaAvantea srl, Laboratory of Reproductive Technologies, Cremona, Italy.ORCID 0000-0003-4498-6230
Elisa HauckeDepartment of Anatomy and Cell Biology, Faculty of Medicine, Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany.
Bernd FischerDepartment of Anatomy and Cell Biology, Faculty of Medicine, Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany.
Alexander Navarrete SantosDepartment of Cardiothoracic Surgery, University Hospital, Halle (Saale), Germany.
Silvia ColleoniAvantea srl, Laboratory of Reproductive Technologies, Cremona, Italy.
Cesare GalliAvantea srl, Laboratory of Reproductive Technologies, Cremona, Italy.
Anne Navarrete SantosDepartment of Anatomy and Cell Biology, Faculty of Medicine, Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany.
Giovanna LazzariAvantea srl, Laboratory of Reproductive Technologies, Cremona, Italy.
Avantea · ITMartin Luther University Halle-Wittenberg · DEUniversity Hospital in Halle · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The accumulation of advanced glycation end products (AGEs) occurs in ageing and in many degenerative diseases as a final outcome of persistent oxidative stress on cells and organs. Environmental alterations taking place during early embryonic development can also lead to oxidative damage, reactive oxygen species (ROS) production, and AGE accumulation. Whether similar mechanisms act on somatic and embryonic stem cells (ESC) exposed to oxidative stress is not known; and therefore, the modelling of oxidative stress in vitro on human ESC has been the focus of this study. We compared changes in N

Indexed as

Antigens, NeoplasmCell DifferentiationCell LineEmbryonic Stem CellsFibroblastsGlycation End Products, AdvancedHumansHuman Umbilical Vein Endothelial CellsHydrogen PeroxideLysineMitogen-Activated Protein KinasesMyocytes, CardiacNeural Stem CellsNeuronsOxidative StressRNA, MessengerAntigens, NeoplasmGlycation End Products, AdvancedHydrogen PeroxideLysineMitogen-Activated Protein KinasesMOK protein, humanN(6)-(1-carboxyethyl)lysineRNA, Messenger

Identifiers

PMID29104727
PMCPMC5623800
OpenAlexW2754260834

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.