Evidence map›Paper›PMID 29104726›Full record

ArticleOxidative medicine and cellular longevity2017

MicroRNA-34a: A Key Regulator in the Hallmarks of Renal Cell Carcinoma.

Eman A Toraih, Afaf T Ibrahiem, Manal S Fawzy, Mohammad H Hussein, Saeed Awad M Al-Qahtani, Aly A M Shaalan

Abstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

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  19. MicroRNA Signature in Renal Cell Carcinoma.Frontiers in oncology · 2020
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Eman A ToraihFaculty of Medicine, Genetics Unit, Department of Histology and Cell Biology, Suez Canal University, P.O. 41522, Ismailia, Egypt.ORCID 0000-0001-9267-3787
Afaf T IbrahiemFaculty of Medicine, Department of Pathology, Mansoura University, Mansoura, Egypt.ORCID 0000-0002-8636-0220
Manal S FawzyFaculty of Medicine, Department of Medical Biochemistry, Suez Canal University, P.O. 41522, Ismailia, Egypt.ORCID 0000-0003-1252-8403
Mohammad H HusseinMinistry of Health, Cairo, Egypt.
Saeed Awad M Al-QahtaniFaculty of Medicine, Department of Physiology, Jazan University, Jazan, Saudi Arabia.
Aly A M ShaalanFaculty of Medicine, Department of Histology and Cell Biology, Suez Canal University, Ismailia, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Renal cell carcinoma (RCC) incidence has increased over the past two decades. Recent studies reported microRNAs as promising biomarkers for early cancer detection, accurate prognosis, and molecular targets for future treatment. This study aimed to evaluate the expression levels of miR-34a and 11 of its bioinformatically selected target genes and proteins to test their potential dysregulation in RCC. Quantitative real-time PCR for miR-34a and its targets;

Indexed as

AdultAgedCarcinogenesisCarcinoma, Renal CellDisease ProgressionFemaleGene Expression ProfilingHumansImmunohistochemistryKidney NeoplasmsMaleMicroRNAsMiddle AgedParaffin EmbeddingYoung AdultMicroRNAsMIRN34 microRNA, human

Identifiers

PMID29104726
PMCPMC5632457

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.