Evidence map›Paper›PMID 29104658›Full record

ArticleExperimental and therapeutic medicine2017

Bacterial keratitis: Photodynamic inactivation reduced experimental inflammation.

Mona Deichelbohrer, Ming-Feng Wu, Berthold Seitz, Dirk Hüttenberger, Matthias W Laschke, Hans-Jochen Foth, Bodo Wonnenberg, Stefan Wagenpfeil, Carola Meier, Markus Bischoff and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. The Effect of Anti-Amoebic Agents and Ce6-PDT onTranslational vision science & technology · 2020
    Article
  5. Non-antibiotic management of bacterial keratitis.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Mona DeichelbohrerInstitute of Anatomy and Cell Biology, Medical Faculty, Saarland University, D-66424 Homburg/Saar, Germany.
Ming-Feng WuDepartment of Ophthalmology, Saarland University Medical Center/UKS, D-66424 Homburg/Saar, Germany.
Berthold SeitzDepartment of Ophthalmology, Saarland University Medical Center/UKS, D-66424 Homburg/Saar, Germany.
Dirk HüttenbergerAPO-CARE Pharma GmbH, D-33647 Bielefeld, Germany.
Matthias W LaschkeInstitute of Clinical and Experimental Surgery, Saarland University, Medical Faculty, D-66424 Homburg/Saar, Germany.
Hans-Jochen FothDepartment of Physics, University of Kaiserslautern, D-67663 Kaiserslautern, Germany.
Bodo WonnenbergInstitute of Anatomy and Cell Biology, Medical Faculty, Saarland University, D-66424 Homburg/Saar, Germany.
Stefan WagenpfeilInstitute for Medical Biometry, Epidemiology and Medical Informatics, Saarland University, D-66424 Homburg/Saar, Germany.
Carola MeierInstitute of Anatomy and Cell Biology, Medical Faculty, Saarland University, D-66424 Homburg/Saar, Germany.
Markus BischoffInstitute of Medical Microbiology and Hygiene, Saarland University, Medical Faculty, D-66424 Homburg/Saar, Germany.
Thomas TschernigInstitute of Anatomy and Cell Biology, Medical Faculty, Saarland University, D-66424 Homburg/Saar, Germany.
Saarland University · DEApocare Pharma (Germany) · DEInstitute of Medical Microbiology and Hygiene · DEUniversity of Kaiserslautern · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The successful treatment of bacterial keratitis remains an unsolved clinical problem. The current study aimed to establish a murine keratitis model and to investigate the effect of chlorin e6 (Ce6) and photodynamic inactivation (PDI) on corneal inflammation. The cornea of anesthetized mice was scratched and covered with a bacterial suspension of

Indexed as

bacterial keratitischlorin e6photodynamic inactivationPseudomonas aeruginosa

Identifiers

PMID29104658
PMCPMC5658727
OpenAlexW2751677408

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.