Evidence map›Paper›PMID 29104594›Full record

ArticleStem cells international2017

Sex Differences of Human Cardiac Progenitor Cells in the Biological Response to TNF-

Elisabetta Straface, Lucrezia Gambardella, Francesca Pagano, Francesco Angelini, Barbara Ascione, Rosa Vona, Elena De Falco, Elena Cavarretta, Raffaele La Russa, Walter Malorni and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Stem cells international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Sex-Related Effects on Cardiac Development and Disease.Journal of cardiovascular development and disease · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Elisabetta StrafaceCenter for Gender-Specific Medicine, Istituto Superiore di Sanità, Rome, Italy.ORCID 0000-0003-0784-9077
Lucrezia GambardellaCenter for Gender-Specific Medicine, Istituto Superiore di Sanità, Rome, Italy.ORCID 0000-0003-3899-5958
Francesca PaganoDepartment of Medical Surgical Sciences and Biotechnologies, "La Sapienza" University of Rome, Rome, Italy.
Francesco AngeliniDepartment of Medical Surgical Sciences and Biotechnologies, "La Sapienza" University of Rome, Rome, Italy.ORCID 0000-0002-0052-6956
Barbara AscioneCenter for Gender-Specific Medicine, Istituto Superiore di Sanità, Rome, Italy.
Rosa VonaCenter for Gender-Specific Medicine, Istituto Superiore di Sanità, Rome, Italy.ORCID 0000-0003-4501-8661
Elena De FalcoDepartment of Medical Surgical Sciences and Biotechnologies, "La Sapienza" University of Rome, Rome, Italy.ORCID 0000-0002-5220-0587
Elena CavarrettaDepartment of Medical Surgical Sciences and Biotechnologies, "La Sapienza" University of Rome, Rome, Italy.ORCID 0000-0003-0221-6000
Raffaele La RussaDepartment of Anatomical, Histological, Forensic and Orthopaedic Sciences, Sapienza University of Rome, Viale Regina Elena 336, 00185 Rome, Italy.ORCID 0000-0003-3433-7122
Walter MalorniCenter for Gender-Specific Medicine, Istituto Superiore di Sanità, Rome, Italy.ORCID 0000-0002-1223-7000
Giacomo FratiDepartment of Medical Surgical Sciences and Biotechnologies, "La Sapienza" University of Rome, Rome, Italy.ORCID 0000-0003-2703-3761
Isotta ChimentiDepartment of Medical Surgical Sciences and Biotechnologies, "La Sapienza" University of Rome, Rome, Italy.ORCID 0000-0002-0865-8814
Sapienza University of Rome · ITIstituto Superiore di Sanità · ITIstituto Neurologico Mediterraneo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adult cardiac progenitor cells (CPCs), isolated as cardiosphere-derived cells (CDCs), represent promising candidates for cardiac regenerative therapy. CDCs can be expanded in vitro manyfolds without losing their differentiation potential, reaching numbers that are appropriate for clinical applications. Since mechanisms of successful CDC survival and engraftment in the damaged myocardium are still critical and unresolved issues, we aimed at deciphering possible key factors capable of bolstering CDC function. In particular, the response and the phenotype of CDCs exposed to low concentrations of the multifunctional cytokine tumor necrosis factor

Identifiers

PMID29104594
PMCPMC5623773
OpenAlexW2754072107

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.