Evidence map›Paper›PMID 29104569›Full record

ArticleFrontiers in microbiology2017

A Linear 19-Mer Plant Defensin-Derived Peptide Acts Synergistically with Caspofungin against

Tanne L Cools, Caroline Struyfs, Jan W Drijfhout, Soňa Kucharíková, Celia Lobo Romero, Patrick Van Dijck, Marcelo H S Ramada, Carlos Bloch, Bruno P A Cammue, Karin Thevissen

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05368948 (The Assessment of Antimicrobial Peptides Against Fungal Infection), which is not on this map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05368948 unknown statusnot on this mapstarted 2022, after this paper: background citation

The Assessment of Antimicrobial Peptides Against Fungal Infection

TypeobservationalSponsorAssiut UniversityRan2022 to 2023Enrolled100ConditionsFungal Infection
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Synergic Effect of the Antimicrobial Peptide ToAP2 and Fluconazole onInternational journal of molecular sciences · 2024
    Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Caspofungin resistance in Candida albicans: genetic factors and synergistic compounds for combination therapies.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2022
    Review
  8. Antimicrobial Peptides with Anti-International journal of molecular sciences · 2022
    Review
  9. Article
  10. Article
  11. Article
  12. Membrane-Interacting Antifungal Peptides.Frontiers in cell and developmental biology · 2021
    Review
  13. Plant-Derived Substances in the Fight Against Infections Caused byInternational journal of molecular sciences · 2020
    Review
  14. Article
  15. Article
  16. Review
  17. Antifungal Peptides as Therapeutic Agents.Frontiers in cellular and infection microbiology · 2020
    Review
  18. Bioactive Peptides Against Fungal Biofilms.Frontiers in microbiology · 2019
    Review
  19. Review
  20. Methodologies forMicrobial cell (Graz, Austria) · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Tanne L CoolsCentre of Microbial and Plant Genetics, KU Leuven, Leuven, Belgium.
Caroline StruyfsCentre of Microbial and Plant Genetics, KU Leuven, Leuven, Belgium.
Jan W DrijfhoutDepartment of Immunohematology and Bloodtransfusion, Leiden University Medical Center, Leiden, Netherlands.
Soňa KucharíkováLaboratory of Molecular Cell Biology, KU Leuven, Leuven, Belgium.
Celia Lobo RomeroLaboratory of Molecular Cell Biology, KU Leuven, Leuven, Belgium.
Patrick Van DijckLaboratory of Molecular Cell Biology, KU Leuven, Leuven, Belgium.
Marcelo H S RamadaGraduate Program in Genomic Sciences and Biotechnology, Catholic University of Brasilia, Brasilia, Brazil.
Carlos BlochMass Spectrometry Laboratory, Embrapa Genetic Resources and Biotechnology, Brasilia, Brazil.
Bruno P A CammueCentre of Microbial and Plant Genetics, KU Leuven, Leuven, Belgium.
Karin ThevissenCentre of Microbial and Plant Genetics, KU Leuven, Leuven, Belgium.
KU Leuven · BEBrazilian Agricultural Research Corporation · BRLeiden University Medical Center · NLVIB-KU Leuven Center for Microbiology · BEVIB-UGent Center for Plant Systems Biology · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Public health problems are associated with device-associated biofilm infections, with

Indexed as

antimicrobial peptidesbiofilmsCandidacathetersfungal infections

Identifiers

PMID29104569
PMCPMC5655031
OpenAlexW2765988139

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.