ArticleFrontiers in neuroscience2017
Antibiotic Driven Changes in Gut Motility Suggest Direct Modulation of Enteric Nervous System.
Article in Frontiers in neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 31 citations in OpenAlex.
- Antibiotic Cocktail Exacerbates Esomeprazole-Induced Intestinal Dysmotility While Ameliorating Gastric Dyspepsia in Mice.Antibiotics (Basel, Switzerland) · 2025Article
- Antibiotic duration and gastric dysmotility in preterm neonates.Journal of pediatric gastroenterology and nutrition · 2024Article
- Squalamine reverses age-associated changes of firing patterns of myenteric sensory neurons and vagal fibres.Communications biology · 2024Article
- What we need to know about the germ-free animal models.AIMS microbiology · 2024Review
- Recent advances in understanding the roles of the enteric nervous system.Faculty reviews · 2022Review
- Mechanistic Insights Into Gut Microbiome Dysbiosis-Mediated Neuroimmune Dysregulation and Protein Misfolding and Clearance in the Pathogenesis of Chronic Neurodegenerative Disorders.Frontiers in neuroscience · 2022Review
- Intestinal microbiota shapes gut physiology and regulates enteric neurons and glia.Microbiome · 2021Article
- Early life interaction between the microbiota and the enteric nervous system.American journal of physiology. Gastrointestinal and liver physiology · 2020Review
- Opposing effects of antibiotics and germ-free status on neuropeptide systems involved in social behaviour and pain regulation.BMC neuroscience · 2020Article
- Sex dependent effects of post-natal penicillin on brain, behavior and immune regulation are prevented by concurrent probiotic treatment.Scientific reports · 2020Article
- Microvesicles from Lactobacillus reuteri (DSM-17938) completely reproduce modulation of gut motility by bacteria in mice.PloS one · 2020Article
- Microbe and host interaction in gastrointestinal homeostasis.Psychopharmacology · 2019Article
- Colonic Motility and Jejunal Vagal Afferent Firing Rates Are Decreased in Aged Adult Male Mice and Can Be Restored by an Aminosterol.Frontiers in neuroscience · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Antibiotic-mediated changes to the intestinal microbiome have largely been assumed to be the basis of antibiotic-induced neurophysiological and behavioral changes. However, relatively little research has addressed whether antibiotics act directly on the host nervous system to produce these changes. We aimed to identify whether acute exposure of the gastrointestinal tract to antibiotics directly modulates neuronally dependent motility reflexes,
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.