Evidence map›Paper›PMID 29104516›Full record

ArticleJournal of biomedical nanotechnology2017

Fluorescence Microscopy Imaging Calibration for Quantifying Nanocarrier Binding to Cells During Shear Flow Exposure.

Abhay Ranganathan, Jessica Campo, Jacob Myerson, Vladimir Shuvaev, Blaine Zern, Vladimir Muzykantov, David M Eckmann

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of biomedical nanotechnology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Abhay RanganathanDepartment of Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Jessica CampoDepartment of Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Jacob MyersonDepartment of Pharmacology, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Vladimir ShuvaevDepartment of Pharmacology, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Blaine ZernDepartment of Pharmacology, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Vladimir MuzykantovDepartment of Pharmacology, University of Pennsylvania, Philadelphia, PA, 19104, USA.
David M EckmannDepartment of Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia, PA, 19104, USA.
University of Pennsylvania · US

Funding

Targeted Microcarrier Design and OptimizationR01EB006818 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI ECKMANN, DAVID M · 2008 to 2016
$3.3M
Bridging multiple scales in modeling targeted drug nanocarrier deliveryU01EB016027 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI ECKMANN, DAVID M, RADHAKRISHNAN, RAVI · 2013 to 2017
$2.7M
NIBIB NIH HHS R01 EB006818NIBIB NIH HHS U01 EB016027
6 · The paper itself

Abstract

Targeted drug delivery is a fast growing industry in healthcare and technologies are being developed for applications utilizing nanocarriers as vehicles for drug transport. As the size scale of these particles becomes further reduced, advanced fluorescence microscopy and image analysis techniques become increasingly important for facilitating our understanding of nanocarrier binding and avidity, thereby establishing the basis for nanocarrier design optimization. While there is a significant body of published work using nanocarriers

Indexed as

Drug Delivery SystemsNanoparticlesCalibrationDrug CarriersMicroscopy, FluorescenceOptical ImagingDrug CarriersBindingCalibrationFluorescence MicroscopyImage AnalysisNanocarrierNanogelQuantitative BindingShear StressTargeted Drug Delivery

Identifiers

PMID29104516
PMCPMC5665578
OpenAlexW2760119026

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.