Evidence map›Paper›PMID 29104511›Full record

ArticleInternational journal of biological sciences2017

ATP2B1 gene Silencing Increases Insulin Sensitivity through Facilitating Akt Activation via the Ca

Yang Long, Ji-Yi Xia, Shao-Wei Chen, Chen-Lin Gao, Guan-Nan Liang, Xue-Mei He, Jian Wu, Chun-Xia Jiang, Xin Liu, Wei Huang and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of biological sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. A novelExperimental biology and medicine (Maywood, N.J.) · 2026
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  5. Diphlorethohydroxycarmalol Isolated fromInternational journal of molecular sciences · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Yang LongDepartment of Endocrinology, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan, P R China.
Ji-Yi XiaKey Laboratory of Medical Electrophysiology of Ministry of Education, Collaborative Innovation Center for Prevention and Treatment of Cardiovascular Disease, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, 646000, Sichuan, P R China.
Shao-Wei ChenMedical Reproduction Center, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan, P R China.
Chen-Lin GaoDepartment of Endocrinology, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan, P R China.
Guan-Nan LiangLaboratory of Endocrinology, Experimental Medicine Center, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan, P R China.
Xue-Mei HeLaboratory of Endocrinology, Experimental Medicine Center, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan, P R China.
Jian WuLaboratory of Endocrinology, Experimental Medicine Center, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan, P R China.
Chun-Xia JiangDepartment of Endocrinology, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan, P R China.
Xin LiuLaboratory of Endocrinology, Experimental Medicine Center, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan, P R China.
Wei HuangDepartment of Endocrinology, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan, P R China.
Qin WanDepartment of Endocrinology, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan, P R China.
Yong XuDepartment of Endocrinology, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan, P R China.
Affiliated Hospital of Southwest Medical University · CNSouthwest Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endothelial cell insulin resistance may be partially responsible for the higher risk of atherosclerosis and cardiovascular disease in populations with insulin resistance and type 2 diabetes mellitus (T2DM). A genome-wide association study revealed a significant association between the ATPase plasma membrane Ca

Indexed as

AnimalsCalciumCalmodulinDiabetes Mellitus, Type 2HumansInsulin ResistanceNitric Oxide Synthase Type IIIPhosphorylationProto-Oncogene Proteins c-aktSignal TransductionCalciumCalmodulinNitric Oxide Synthase Type IIIProto-Oncogene Proteins c-aktATPase plasma membrane Ca2+ transporting 1CalciumCalmodulin.Endothelial Insulin ResistancePlasma Membrane Calcium ATPase 1

Identifiers

PMID29104511
PMCPMC5666335
OpenAlexW2754346643

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.