ReviewInternational journal of biological sciences2017
The Emerging Roles of Microparticles in Diabetic Nephropathy.
Review in International journal of biological sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Evidence of cancer: a systematic review of metabolomics in extracellular vesicles for cancer biomarker detection.Metabolomics : Official journal of the Metabolomic Society · 2025Pooled it
- The interplay between endothelial cell dysfunction and podocyte injury in diabetic nephropathy: a comprehensive review of current evidence.American journal of translational research · 2025Review
- Identification of key genes in diabetic nephropathy based on lipid metabolism.Experimental and therapeutic medicine · 2024Article
- The role of miRNAs carried by extracellular vesicles in type 2 diabetes and its complications.Journal of diabetes · 2023Review
- Proteomics of Plasma and Plasma-Treated Podocytes: Application to Focal and Segmental Glomerulosclerosis.International journal of molecular sciences · 2023Article
- The Role of Platelets in Diabetic Kidney Disease.International journal of molecular sciences · 2022Review
- Src Activation Aggravates Podocyte Injury in Diabetic NephropathyFrontiers in pharmacology · 2022Article
- LncRNA HCP5 knockdown inhibits high glucose-induced excessive proliferation, fibrosis and inflammation of human glomerular mesangial cells by regulating the miR-93-5p/HMGA2 axis.BMC endocrine disorders · 2021Article
- Horizontal MicroRNA Transfer by Platelets - Evidence and Implications.Frontiers in physiology · 2021Review
- The role of microvesicles containing microRNAs in vascular endothelial dysfunction.Journal of cellular and molecular medicine · 2019Review
- The role of microvesicles and its active molecules in regulating cellular biology.Journal of cellular and molecular medicine · 2019Review
- Mechanism and Consequences of The Impaired Hif-1α Response to Hypoxia in Human Proximal Tubular HK-2 Cells Exposed to High Glucose.Scientific reports · 2019Article
- Article
- Saturated fatty acid stimulates production of extracellular vesicles by renal tubular epithelial cells.Molecular and cellular biochemistry · 2019Article
- The role of extracellular vesicles in renal fibrosis.Cell death & disease · 2019Review
- High glucose-induced endothelial microparticles increase adhesion molecule expression on endothelial cells.Diabetology international · 2019Article
- HIF1α deletion facilitates adipose stem cells to repair renal fibrosis in diabetic mice.In vitro cellular & developmental biology. Animal · 2018Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microparticles (MPs) are a type of extracellular vesicles (EVs) shed from the outward budding of plasma membranes during cell apoptosis and/or activation. These microsized particles then release specific contents (e.g., lipids, proteins, microRNAs) which are active participants in a wide range of both physiological and pathological processes at the molecular level, e.g., coagulation and angiogenesis, inflammation, immune responses. Research limitations, such as confusing nomenclature and overlapping classification, have impeded our comprehension of these tiny molecules. Diabetic nephropathy (DN) is currently the greatest contributor to end-stage renal diseases (ESRD) worldwide, and its public health impact will continue to grow due to the persistent increase in the prevalence of diabetes mellitus (DM). MPs have recently been considered as potentially involved in DN onset and progression, and this review juxtaposes some of the research updates about the possible mechanisms from several relevant aspects and insights into the therapeutic perspectives of MPs in clinical management and pharmacological treatment of DN patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.